Rac GTPase Activating Protein 1 Products
(Rac GTPase Activating Protein 1 (RACGAP1))
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The protein encoded by this gene belongs to the GTPase-activating protein (GAP) family. GAPs bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, GAPs negatively regulate Rho-mediated signals. This protein plays a regulatory role in initiation of cytokinesis, controlling cell growth and differentiation of hematopoietic cells, regulating spermatogenesis, and in neuronal proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011].
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Featured Rac GTPase Activating Protein 1 Categories
Rac GTPase Activating Protein 1 Antibodies
High quality antibodies with extensive validation data.
Rac GTPase Activating Protein 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Rac GTPase Activating Protein 1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Rac GTPase Activating Protein 1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, IF, FACS
Validations
- (7)
Cat. No.
ABIN184690
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), ICC
Validations
- (1)
- (5)
Cat. No.
ABIN2856889
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
- (5)
Cat. No.
ABIN565414
Quantity
100 μg
Datasheet
Datasheet
Recommended Rac GTPase Activating Protein 1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962157
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959034
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959035
Quantity
96 tests
Datasheet
Datasheet
Recommended Rac GTPase Activating Protein 1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317259
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7397972
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3095022
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Rac GTPase Activating Protein 1 products
: "CDK11p58-cyclin L1β regulates abscission site assembly." in: The Journal of biological chemistry, Vol. 294, Issue 49, pp. 18639-18649, (2019) (PubMed).: "Overexpression of Rac GTPase Activating Protein 1 Contributes to Proliferation of Cancer Cells by Reducing Hippo Signaling to Promote Cytokinesis." in: Gastroenterology, Vol. 155, Issue 4, pp. 1233-1249.e22, (2018) (PubMed).
: "Eph-mediated tyrosine phosphorylation of citron kinase controls abscission." in: The Journal of cell biology, Vol. 214, Issue 5, pp. 555-69, (2017) (PubMed).
: "Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis." in: Nature, Vol. 492, Issue 7428, pp. 276-9, (2012) (PubMed).
: "Upregulation of Rac GTPase-activating protein 1 is significantly associated with the early recurrence of human hepatocellular carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 18, pp. 6040-51, (2011) (PubMed).
: "Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation." in: PLoS biology, Vol. 7, Issue 5, pp. e1000110, (2009) (PubMed).
: "Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells." in: PLoS biology, Vol. 7, Issue 5, pp. e1000111, (2009) (PubMed).
: "Centralspindlin regulates ECT2 and RhoA accumulation at the equatorial cortex during cytokinesis." in: Journal of cell science, Vol. 119, Issue Pt 1, pp. 104-14, (2005) (PubMed).
: "A hemopoietic specific gene encoding a small GTP binding protein is overexpressed during T cell activation." in: Biochemical and biophysical research communications, Vol. 175, Issue 2, pp. 451-8, (1991) (PubMed).
Synonyms and alternative names related to Rac GTPase Activating Protein 1
Rac GTPase activating protein 1 (RACGAP1), Rac GTPase activating protein 1 (racgap1), rac GTPase-activating protein 1 (RACGAP1), Rac GTPase activating protein 1 L homeolog (racgap1.L), Rac GTPase activating protein 1 L homeolog (racgap1.2.L), Rac GTPase activating protein 1 (racgap1.2), RAS p21 protein activator 1 (Rasa1), Rac GTPase-activating protein 1 (Racgap1), Rac GTPase activating protein 1 (Racgap1), si:ch1073-416j23.1 (si:ch1073-416j23.1), AI227039, AI327394, Band25, cyk-4, CYK4, Gap, GAPX, gtl11, GTPase, HsCYK-4, ID-GAP, id-gap, MGC121578, MgcRacGAP, mgcracgap, mKIAA1478, RACGAP1, Rasa, RasGAP, wu:fb92c08, zgc:77839Protein level used designations for Rac GTPase Activating Protein 1
- GTPase activating protein
- male germ cell RacGap
- protein CYK4 homolg
- protein CYK4 homolog
- rac GTPase-activating protein 1
- Rac GTPase-activating protein 1
- Rac GTPase activating protein 1
- rac GTPase-activating protein 1-like
- GTPase-activating protein
- p120-rasGAP
- GAP
- RAS p21 protein activator 1
- p120GAP
- ras GTPase-activating protein 1
- rasGAP
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