RABGEF1 Products
(RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
Categories
RABGEF1 forms a complex with rabaptin-5 (RABPT5\; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A\; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).[supplied by OMIM, Mar 2010].
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Featured RABGEF1 Categories
RABGEF1 Antibodies
High quality antibodies with extensive validation data.
RABGEF1 ELISA Kits
Reliable ELISA kits for a wide range of species.
RABGEF1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RABGEF1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7167001
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN525977
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Chicken, Cow, Dog, Goat, Guinea Pig, Horse, Human, Monkey, Mouse, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (1)
Cat. No.
ABIN6743794
Quantity
100 μL
Datasheet
Datasheet
Recommended RABGEF1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1154281
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1154282
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1154280
Quantity
96 tests
Datasheet
Datasheet
Recommended RABGEF1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317236
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3130347
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN5711903
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our RABGEF1 products
: "Endosomal Rab cycles regulate Parkin-mediated mitophagy." in: eLife, Vol. 7, (2018) (PubMed).: "Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke." in: Stroke, Vol. 47, Issue 12, pp. 3022-3031, (2016) (PubMed).
: "A novel binding protein composed of homophilic tetramer exhibits unique properties for the small GTPase Rab5." in: The Journal of biological chemistry, Vol. 277, Issue 5, pp. 3412-8, (2002) (PubMed).
: "Selective membrane recruitment of EEA1 suggests a role in directional transport of clathrin-coated vesicles to early endosomes." in: The Journal of biological chemistry, Vol. 275, Issue 6, pp. 3745-8, (2000) (PubMed).
: "A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function." in: Cell, Vol. 90, Issue 6, pp. 1149-59, (1997) (PubMed).
Synonyms and alternative names related to RABGEF1
RAB guanine nucleotide exchange factor (GEF) 1 (Rabgef1), RAB guanine nucleotide exchange factor 1 (Rabgef1), RAB guanine nucleotide exchange factor 1 (RABGEF1), RAB guanine nucleotide exchange factor (GEF) 1 L homeolog (rabgef1.L), Rab5ef, rabex-5, Rabex5, RABEX5, rabgef1, Rin2Protein level used designations for RABGEF1
- Rab5 exchange factor
- Ras negative regulator Rabex-5
- Ras negative regulator Rabex-5/Rin2
- rab5 GDP/GTP exchange factor
- rabex-5
- RAP1
- rabaptin-5-associated exchange factor for Rab5
- Rab5 guanine nucleotide exchange factor Rabex-5
- RAB guanine nucleotide exchange factor (GEF) 1
- Rab5 GDP/GTP exchange factor
- BTB/POZ domain-containing protein KCTD7
- RAB guanine nucleotide exchange factor (GEF) 1 L homeolog
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