RAB27A Products
(RAB27A, Member RAS Oncogene Family (RAB27A))
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The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008].
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Featured RAB27A Categories
RAB27A Antibodies
High quality antibodies with extensive validation data.
RAB27A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended RAB27A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), RNAi
Validations
- (8)
- (6)
Cat. No.
ABIN562560
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (5)
Cat. No.
ABIN2683011
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (5)
Cat. No.
ABIN3015733
Quantity
100 μL
Datasheet
Datasheet
Recommended RAB27A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124745
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN666995
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317084
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our RAB27A products
: "Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins." in: Nature communications, Vol. 11, Issue 1, pp. 3495, (2020) (PubMed).: "MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation." in: Immunity, Vol. 47, Issue 1, pp. 51-65.e7, (2017) (PubMed).
: "Isolation of Intact and Functional Melanosomes from the Retinal Pigment Epithelium." in: PLoS ONE, Vol. 11, Issue 8, pp. e0160352, (2017) (PubMed).
: "Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma." in: Journal of translational medicine, Vol. 14, pp. 56, (2016) (PubMed).
: "Rab27a GTPase modulates L-type Ca2+ channel function via interaction with the II-III linker of CaV1.3 subunit." in: Cellular signalling, Vol. 27, Issue 11, pp. 2231-40, (2016) (PubMed).
: "Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA)." in: Molecular cancer, Vol. 14, pp. 133, (2015) (PubMed).
: "Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion." in: PLoS ONE, Vol. 10, Issue 5, pp. e0125596, (2015) (PubMed).
: "Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding." in: The Journal of allergy and clinical immunology, (2014) (PubMed).
: "Activated Cdc42-bound IQGAP1 determines the cellular endocytic site." in: Molecular and cellular biology, Vol. 33, Issue 24, pp. 4834-43, (2013) (PubMed).
: "Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. ..." in: Nature medicine, Vol. 18, Issue 6, pp. 883-91, (2012) (PubMed).
Synonyms and alternative names related to RAB27A
RAB27A, member RAS oncogene family L homeolog (rab27a.L), RAB27A, member RAS oncogene family (RAB27A), RAB27A, member RAS oncogene family (rab27a), RAB27A, member RAS oncogene family S homeolog (rab27a.S), RAB27A, member RAS oncogene family (Rab27a), 2210402C08Rik, 2410003M20Rik, 4933437C11Rik, ash, gs2, GS2, hst18676, HsT18676, MGC80943, MGC89827, rab27, RAB27, RAB27A, ram, RAM, zgc:114135Protein level used designations for RAB27A
- RAB27A, member RAS oncogene family
- Ras-related protein Rab-27A
- rab27a, member ras oncogene family
- ras-related protein Rab-27A
- GTP-binding protein Ram
- rab-27
- member RAS oncogene family, RAB27A
- ashen
- low Mr GTP-binding protein
- ram p25
- RAS oncogene family member
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