QPRT Products
(Quinolinate Phosphoribosyltransferase (QPRT))
Categories
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq, Jul 2008].
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Featured QPRT Categories
QPRT Antibodies
High quality antibodies with extensive validation data.
QPRT ELISA Kits
Reliable ELISA kits for a wide range of species.
QPRT Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended QPRT Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN565099
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (2)
Cat. No.
ABIN565098
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (3)
Cat. No.
ABIN525200
Quantity
50 μg
Datasheet
Datasheet
Recommended QPRT ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969810
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969809
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959018
Quantity
96 tests
Datasheet
Datasheet
Recommended QPRT Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124728
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317005
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1317007
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our QPRT products
: "Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA." in: Cancer & metabolism, Vol. 6, pp. 1, (2018) (PubMed).: "The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress." in: Cancer research, Vol. 73, Issue 11, pp. 3225-34, (2013) (PubMed).
: "QPRT: a potential marker for follicular thyroid carcinoma including minimal invasive variant; a gene expression, RNA and immunohistochemical study." in: BMC cancer, Vol. 9, pp. 93, (2009) (PubMed).
: "Characterization of the kynurenine pathway in human neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 47, pp. 12884-92, (2007) (PubMed).
Synonyms and alternative names related to QPRT
quinolinate phosphoribosyltransferase (ECs0113), quinolinate phosphoribosyltransferase (nadC), quinolinate phosphoribosyltransferase (VP2522), nicotinate-nucleotide pyrophosphorylase (STY0167), nicotinate-nucleotide diphosphorylase (nadC), nicotinate-nucleotide diphosphorylase (BJE04_RS13210), carboxylating (nadC), quinolinate phosphoribosyltransferase (QPRT), quinolinate phosphoribosyltransferase (Qprt), 2410027J01Rik, AI647766, ECK0108, JW0105, QPRTase, VF2184Protein level used designations for QPRT
- quinolinate phosphoribosyltransferase
- QAPRTase
- nicotinate-nucleotide pyrophosphorylase (carboxylating)
- nicotinate-nucleotide pyrophosphorylase [carboxylating]
- nicotinate-nucleotide pyrophosphorylase
- QPRTase
- quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating))
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