PYM Products
(Partner of Y14 and mago (WIBG))
Categories
Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post- transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions (By similarity).
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Featured PYM Categories
PYM Antibodies
High quality antibodies with extensive validation data.
PYM Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PYM Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN654666
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
- (1)
Cat. No.
ABIN6750448
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Horse, Human, Monkey, Pig, Xenopus laevis
Application
WB
Validations
- (1)
Cat. No.
ABIN6746847
Quantity
100 μL
Datasheet
Datasheet
Recommended PYM Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1325328
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN1097293
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2132576
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our PYM products
: "Identification of antiviral roles for the exon-junction complex and nonsense-mediated decay in flaviviral infection." in: Nature microbiology, Vol. 4, Issue 6, pp. 985-995, (2019) (PubMed).: "CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation." in: Genes & development, Vol. 29, Issue 21, pp. 2225-30, (2015) (PubMed).
Synonyms and alternative names related to PYM
Partner of Y14 and Mago (Pym), Wibg protein (wibg), PYM homolog 1, exon junction complex associated factor L homeolog (pym1.L), PYM homolog 1, exon junction complex associated factor (PYM1), PYM homolog 1, exon junction complex associated factor (Pym1), PYM homolog 1, exon junction complex associated factor (pym1), A030010B05Rik, BEST:HL05757, CG10330, CG30176, Dmel\\CG30176, PYM, Pym, UD3, zgc:65891, zgc:77281Protein level used designations for PYM
- CG30176-PA
- undefined 3
- wibg-PA
- Protein wibg homolog
- partner of Y14 and mago
- protein wibg homolog
Did you look for something else?
- PYKA
- PYHIN1
- PYGO2
- PYGO1
- PYGL
- PYGB
- Pydc3
- PYDC1
- PYCRL
- PYCR2
- PYCR1
- PYCARD
- PXT1
- PXR1
- PXMP4
- PXMP2
- PXK
- PXDNL
- PXDC1
- PWWP2B
- PYR1
- Pyranose Oxidase
- PYRB
- PYRDA
- PYRDB
- Pyridinoline
- Pyrin Domain Containing 2
- Pyroglutamate Aminopeptidase
- Pyrophosphatase (Inorganic) 1
- Pyrophosphatase 2
- PYROXD1
- PYROXD2
- Pyruvate Carboxylase 1
- Pyruvate Dehydrogenase (Lipoamide) alpha 1
- Pyruvate Kinase
- Pyruvate Kinase, Muscle
- Pyruvate Oxidase
- PYURF
- PYY3
- PZP
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