PVRL4 Products
(Poliovirus Receptor-Related 4 (PVRL4))
Categories
This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011].
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Featured PVRL4 Categories
PVRL4 Antibodies
High quality antibodies with extensive validation data.
PVRL4 ELISA Kits
Reliable ELISA kits for a wide range of species.
PVRL4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PVRL4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (5)
Cat. No.
ABIN7237516
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7161114
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN1387848
Quantity
100 μL
Datasheet
Datasheet
Recommended PVRL4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958676
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN5510701
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730769
Quantity
96 tests
Datasheet
Datasheet
Recommended PVRL4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7275314
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275306
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275313
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PVRL4 products
: "Over-expression of Nectin-4 promotes progression of esophageal cancer and correlates with poor prognosis of the patients." in: Cancer cell international, Vol. 19, pp. 106, (2019) (PubMed).: "Probing Morbillivirus Antisera Neutralization Using Functional Chimerism between Measles Virus and Canine Distemper Virus Envelope Glycoproteins." in: Viruses, Vol. 11, Issue 8, (2019) (PubMed).
: "Ectodomain shedding of the cell adhesion molecule Nectin-4 in ovarian cancer is mediated by ADAM10 and ADAM17." in: The Journal of biological chemistry, Vol. 292, Issue 15, pp. 6339-6351, (2017) (PubMed).
: "Expression of canine distemper virus receptor nectin-4 in the central nervous system of dogs." in: Scientific reports, Vol. 7, Issue 1, pp. 349, (2017) (PubMed).
: "Measles virus infection of human keratinocytes: Possible link between measles and atopic dermatitis." in: Journal of dermatological science, Vol. 86, Issue 2, pp. 97-105, (2017) (PubMed).
: "A Novel Nectin-mediated Cell Adhesion Apparatus That Is Implicated in Prolactin Receptor Signaling for Mammary Gland Development." in: The Journal of biological chemistry, Vol. 291, Issue 11, pp. 5817-31, (2016) (PubMed).
: "Oncolytic measles virus expressing the sodium iodide symporter to treat drug-resistant ovarian cancer." in: Cancer research, Vol. 75, Issue 1, pp. 22-30, (2015) (PubMed).
: "Nectin-4 expression contributes to tumor proliferation, angiogenesis and patient prognosis in human pancreatic cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 30, (2015) (PubMed).
: "SLAM- and nectin-4-independent noncytolytic spread of canine distemper virus in astrocytes." in: Journal of virology, Vol. 89, Issue 10, pp. 5724-33, (2015) (PubMed).
: "Nectin-4 mutations causing ectodermal dysplasia with syndactyly perturb the rac1 pathway and the kinetics of adherens junction formation." in: The Journal of investigative dermatology, Vol. 134, Issue 8, pp. 2146-2153, (2014) (PubMed).
Synonyms and alternative names related to PVRL4
nectin cell adhesion molecule 4 (NECTIN4), nectin cell adhesion molecule 4 (nectin4), nectin cell adhesion molecule 4 (Nectin4), 1200017F15Rik, EDSS1, LNIR, nectin-4, Prr4, PRR4, PVRL4, RGD1559826, si:ch211-155e24.1Protein level used designations for PVRL4
- poliovirus receptor-related 4
- poliovirus receptor-related protein 4-like
- ig superfamily receptor LNIR
- nectin 4
- nectin-4
- poliovirus receptor-related protein 4
- Ig superfamily receptor LNIR
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