PVRL2 Products
(Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
Categories
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Featured PVRL2 Categories
PVRL2 Antibodies
High quality antibodies with extensive validation data.
PVRL2 ELISA Kits
Reliable ELISA kits for a wide range of species.
PVRL2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PVRL2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7441772
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS, ELISA
Validations
- (4)
Cat. No.
ABIN5611344
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (4)
Cat. No.
ABIN562545
Quantity
100 μg
Datasheet
Datasheet
Recommended PVRL2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969439
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1116602
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4883871
Quantity
96 tests
Datasheet
Datasheet
Recommended PVRL2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7275309
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275317
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275305
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PVRL2 products
: "CD226 regulates natural killer cell antitumor responses via phosphorylation-mediated inactivation of transcription factor FOXO1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 50, pp. E11731-E11740, (2019) (PubMed).: "Laquinimod, a prototypic quinoline-3-carboxamide and aryl hydrocarbon receptor agonist, utilizes a CD155-mediated natural killer/dendritic cell interaction to suppress CNS autoimmunity." in: Journal of neuroinflammation, Vol. 16, Issue 1, pp. 49, (2019) (PubMed).
: "The Ubiquitin-proteasome pathway regulates Nectin2/CD112 expression and impairs NK cell recognition and killing." in: European journal of immunology, Vol. 49, Issue 6, pp. 873-883, (2019) (PubMed).
: "Expression of ligands for activating natural killer cell receptors on cell lines commonly used to assess natural killer cell function." in: BMC immunology, Vol. 20, Issue 1, pp. 8, (2019) (PubMed).
: "Nectin-2 in ovarian cancer: How is it expressed and what might be its functional role?" in: Cancer science, Vol. 110, Issue 6, pp. 1872-1882, (2019) (PubMed).
: "Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model." in: Scientific reports, Vol. 9, Issue 1, pp. 10840, (2019) (PubMed).
: "Cultivation and characterization of pterygium as an ex vivo study model for disease and therapy." in: Contact lens & anterior eye : the journal of the British Contact Lens Association, Vol. 40, Issue 5, pp. 283-292, (2018) (PubMed).
: "Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity." in: Nature immunology, Vol. 19, Issue 7, pp. 723-732, (2018) (PubMed).
: "Human NK Cells Lyse Th2-Polarizing Dendritic Cells via NKp30 and DNAM-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 201, Issue 7, pp. 2028-2041, (2018) (PubMed).
: "Innate immune activating ligand SUMOylation affects tumor cell recognition by NK cells." in: Scientific reports, Vol. 7, Issue 1, pp. 10445, (2017) (PubMed).
Synonyms and alternative names related to PVRL2
nectin cell adhesion molecule 2 (Nectin2), nectin cell adhesion molecule 2 (NECTIN2), AI325026, AI987993, Cd112, CD112, HVEB, MPH, nectin-2, prr2, PRR2, Pvr, PVRR2, PvsProtein level used designations for PVRL2
- poliovirus receptor-related protein 2
- herpes virus entry mediator B
- herpesvirus entry mediator B
- hveB
- mHveB
- murine herpes virus entry protein B
- murine herpesvirus entry protein B
- poliovirus receptor homolog
- poliovirus sensitivity
- nectin-2
- poliovirus receptor related 2
- poliovirus receptor-related 2 (herpesvirus entry mediator B)
- herpesvirus entry protein B
- poliovirus receptor-like 2
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