PVRL1 Products
(Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
Categories
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009].
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Featured PVRL1 Categories
PVRL1 Antibodies
High quality antibodies with extensive validation data.
PVRL1 ELISA Kits
Reliable ELISA kits for a wide range of species.
PVRL1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PVRL1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, FACS, IHC, IF, LCI, ICC
Validations
- (5)
Cat. No.
ABIN7043440
Quantity
25 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN519549
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
Cat. No.
ABIN519548
Quantity
50 μg
Datasheet
Datasheet
Recommended PVRL1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969437
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969438
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958675
Quantity
96 tests
Datasheet
Datasheet
Recommended PVRL1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7275307
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275308
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN6952290
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PVRL1 products
: "Specific association of glycoprotein B with lipid rafts during herpes simplex virus entry." in: Journal of virology, Vol. 77, Issue 17, pp. 9542-52, (2003) (PubMed).: "Disruption of adherens junctions liberates nectin-1 to serve as receptor for herpes simplex virus and pseudorabies virus entry." in: Journal of virology, Vol. 76, Issue 14, pp. 7203-8, (2002) (PubMed).
: "Novel, soluble isoform of the herpes simplex virus (HSV) receptor nectin1 (or PRR1-HIgR-HveC) modulates positively and negatively susceptibility to HSV infection." in: Journal of virology, Vol. 75, Issue 12, pp. 5684-91, (2001) (PubMed).
Synonyms and alternative names related to PVRL1
nectin cell adhesion molecule 1 (NECTIN1), nectin-1 (LOC100145553), Poliovirus receptor-related protein 1 (pvrl1), nectin cell adhesion molecule 1 (nectin1), nectin cell adhesion molecule 1 (Nectin1), poliovirus receptor-related 1 (herpesvirus entry mediator C) (PVRL1), nectin cell adhesion molecule 2 L homeolog (nectin2.L), AI835281, AW549174, CD111, Cd111, cd111, cd112, CLPED1, clped1, ED4, ed4, HIgR, higr, hveb, HVEC, HveC, hvec, nectin-1, nectin-2, OFC7, ofc7, PRR, prr, PRR1, prr1, prr2, PVRL1, pvrl1, pvrl2, pvrl2.L, PVRR, pvrr, PVRR1, pvrr1, pvrr2, SK-12, sk-12Protein level used designations for PVRL1
- ectodermal dysplasia 4 (Margarita Island type)
- herpes virus entry mediator C
- herpesvirus Ig-like receptor
- nectin 1
- poliovirus receptor-like 1
- poliovirus receptor-related protein 1
- poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin)
- poliovirus receptor-related 1 (herpesvirus entry mediator C)
- Poliovirus receptor-related protein 1
- herpesvirus entry mediator C
- nectin-1 alpha
- nectin-1 delta
- nectin)
- poliovirus receptor-related 1 (herpesvirus entry mediator C
- nectin-1
- poliovirus receptor-related 1
- nectin
- poliovirus receptor related protein
- nectin 2
- nectin cell adhesion molecule 2 L homeolog
- nectin-2alpha
- poliovirus receptor-related 2 (herpesvirus entry mediator B) L homeolog
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