Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 Products
(Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3))
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The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008].
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Featured Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 Categories
Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 Antibodies
High quality antibodies with extensive validation data.
Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p)
Validations
- (5)
Cat. No.
ABIN3187746
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rabbit
Application
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN705866
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7162443
Quantity
100 μL
Datasheet
Datasheet
Recommended Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313808
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3122134
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3098729
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 products
: "The role of ATP signalling in response to mechanical stimulation studied in T24 cells using new microphysiological tools." in: Journal of cellular and molecular medicine, Vol. 22, Issue 4, pp. 2319-2328, (2018) (PubMed).: "Epigallocatechin-3-gallate alleviates bladder overactivity in a rat model with metabolic syndrome and ovarian hormone deficiency through mitochondria apoptosis pathways." in: Scientific reports, Vol. 8, Issue 1, pp. 5358, (2018) (PubMed).
: "Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling." in: PLoS genetics, Vol. 12, Issue 11, pp. e1006442, (2016) (PubMed).
: "The expression of Toll-like receptor 4, 7 and co-receptors in neurochemical sub-populations of rat trigeminal ganglion sensory neurons." in: Neuroscience, Vol. 310, pp. 686-98, (2015) (PubMed).
: "Hedgehog pathway blockade with the cancer drug LDE225 disrupts taste organs and taste sensation." in: Journal of neurophysiology, Vol. 113, Issue 3, pp. 1034-40, (2015) (PubMed).
: "Lidocaine preferentially inhibits the function of purinergic P2X7 receptors expressed in Xenopus oocytes." in: Anesthesia and analgesia, Vol. 120, Issue 3, pp. 597-605, (2015) (PubMed).
: "Correlation between urothelial differentiation and sensory proteins P2X3, P2X5, TRPV1, and TRPV4 in normal urothelium and papillary carcinoma of human bladder." in: BioMed research international, Vol. 2014, pp. 805236, (2014) (PubMed).
: "Spontaneous firing and evoked responses of spinal nociceptive neurons are attenuated by blockade of P2X3 and P2X2/3 receptors in inflamed rats." in: Journal of neuroscience research, (2012) (PubMed).
: "Light-evoked somatosensory perception of transgenic rats that express channelrhodopsin-2 in dorsal root ganglion cells." in: PLoS ONE, Vol. 7, Issue 3, pp. e32699, (2012) (PubMed).
: "Multifunctional core-shell nanoparticles: discovery of previously invisible biomarkers." in: Journal of the American Chemical Society, Vol. 133, Issue 47, pp. 19178-88, (2011) (PubMed).
Synonyms and alternative names related to Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3
purinergic receptor P2X 3 (P2RX3), purinergic receptor P2X 3 (P2rx3), purinergic receptor P2X, ligand-gated ion channel, 3 (P2rx3), purinergic receptor P2X, ligand-gated ion channel, 3a (p2rx3a), purinergic receptor P2X, ligand-gated ion channel, 3b (p2rx3b), 4930513E20Rik, fb99b08, P2RX3, p2rx3, P2X3, p2x3, p2xr3.2, wu:fb99b08, zfP2X3, zgc:110486, zP2X3, zP2X3.2Protein level used designations for Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3
- ATP receptor
- P2X purinoceptor 3
- P2X receptor, subunit 3
- purinergic receptor P2X3
- purinoceptor P2X3
- P2X3
- purinergic receptor P2X, ligand-gated ion channel, 3
- P2X3 purinoceptor
- zP2X3.1
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