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PTPRT Products

(Receptor Protein Tyrosine Phosphatase (PTPRT))

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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008].

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Featured PTPRT Categories

PTPRT Antibodies

High quality antibodies with extensive validation data.

PTPRT ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended PTPRT Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7002666
Quantity 20 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN185288
Quantity 100 μg
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6748188
Quantity 100 μL
Datasheet Datasheet

Recommended PTPRT ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1154957
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1154958
Quantity 96 tests
Datasheet Datasheet

Latest Publications for our PTPRT products

Yu, Becka, Zhang, Zhang, Brady-Kalnay, Wang: "Tumor-derived extracellular mutations of PTPRT /PTPrho are defective in cell adhesion." in: Molecular cancer research : MCR, Vol. 6, Issue 7, pp. 1106-13, (2008) (PubMed).

Zhang, Guo, Yu, Possemato, Chen, Zheng, Polakiewicz, Kinzler, Vogelstein, Velculescu, Wang: "Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 10, pp. 4060-4, (2007) (PubMed).

Besco, Hooft van Huijsduijnen, Frostholm, Rotter: "Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT)." in: Brain research, Vol. 1116, Issue 1, pp. 50-7, (2006) (PubMed).

Wang, Shen, Parsons, Bardelli, Sager, Szabo, Ptak, Silliman, Peters, van der Heijden, Parmigiani, Yan, Wang, Riggins, Powell, Willson, Markowitz, Kinzler, Vogelstein, Velculescu: "Mutational analysis of the tyrosine phosphatome in colorectal cancers." in: Science (New York, N.Y.), Vol. 304, Issue 5674, pp. 1164-6, (2004) (PubMed).

Synonyms and alternative names related to PTPRT

protein tyrosine phosphatase, receptor type T (PTPRT), protein tyrosine phosphatase, receptor type, T (Ptprt), mKIAA0283, RPTP-rfo, RPTPrho

Protein level used designations for PTPRT

  • R-PTP-T
  • RPTP-rho
  • receptor protein tyrosine phosphatase
  • receptor-type tyrosine-protein phosphatase T
  • receptor-type tyrosine-protein phosphatase rho
  • RPTPmam4
  • mRPTPrho
  • receptor protein tyrosine phosphatase-rho
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