PTPRA Products
(Protein tyrosine Phosphatase, Receptor Type, A (PTPRA))
Categories
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq, Jul 2008].
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Featured PTPRA Categories
PTPRA Antibodies
High quality antibodies with extensive validation data.
PTPRA ELISA Kits
Reliable ELISA kits for a wide range of species.
PTPRA Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PTPRA Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN1682399
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Bat, Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit
Application
IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN1049270
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN1049272
Quantity
50 μg
Datasheet
Datasheet
Recommended PTPRA ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951512
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1154921
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1154922
Quantity
96 tests
Datasheet
Datasheet
Recommended PTPRA Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419442
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419745
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
Cat. No.
ABIN7509248
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our PTPRA products
: "Protein tyrosine-phosphatase expression profiling in gastric cancer tissues." in: Cancer letters, Vol. 242, Issue 1, pp. 95-103, (2006) (PubMed).: "Protein-tyrosine phosphatase alpha, RPTP alpha, is a Helicobacter pylori VacA receptor." in: The Journal of biological chemistry, Vol. 278, Issue 21, pp. 19183-9, (2003) (PubMed).
: "Receptor protein tyrosine phosphatase alpha signaling is involved in androgen depletion-induced neuroendocrine differentiation of androgen-sensitive LNCaP human prostate cancer cells." in: Oncogene, Vol. 22, Issue 43, pp. 6704-16, (2003) (PubMed).
: "The protein tyrosine phosphatase alpha modifies insulin secretion in INS-1E cells." in: Biochemical and biophysical research communications, Vol. 311, Issue 2, pp. 361-4, (2003) (PubMed).
: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).
: "Expression of receptor-like protein tyrosine phosphatase alpha in rat embryo fibroblasts activates mitogen-activated protein kinase and c-Jun." in: The Journal of biological chemistry, Vol. 269, Issue 37, pp. 23302-9, (1994) (PubMed).
: "Cell transformation and activation of pp60c-src by overexpression of a protein tyrosine phosphatase." in: Nature, Vol. 359, Issue 6393, pp. 336-9, (1992) (PubMed).
: "Cloning and expression of a widely expressed receptor tyrosine phosphatase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 16, pp. 6112-6, (1990) (PubMed).
Synonyms and alternative names related to PTPRA
protein tyrosine phosphatase, receptor type A (PTPRA), protein tyrosine phosphatase, receptor type A (ptpra), protein tyrosine phosphatase, receptor type, A (PTPRA), protein tyrosine phosphatase, receptor type, A (Ptpra), protein tyrosine phosphatase, receptor type, A (ptpra), protein tyrosine phosphatase, receptor type A S homeolog (ptpra.S), heptp, HEPTP, hlpr, HLPR, hptpa, HPTPA, hptpalpha, HPTPalpha, lrp, LRP, ptpa, PTPA, Ptpa, ptpa-a, Ptpalpha, PTPRA, ptprl2, PTPRL2, r-ptp-alpha, R-PTP-alpha, rptpa, RPTPA, Rptpalpha, RPTP[a], Rptra, Rptralpha, zf-RPTP[a]Protein level used designations for PTPRA
- protein tyrosine phosphatase, receptor type, A
- receptor-type tyrosine-protein phosphatase alpha-like
- Leukocyte common antigen-related peptide (protein tyrosine phosphate)
- PTPLCA-related phosphatase
- PTPase-alpha
- protein tyrosine phosphatase, receptor type, alpha polypeptide
- protein-tyrosine phosphatase alpha
- receptor-type tyrosine-protein phosphatase alpha
- tyrosine phosphatase alpha
- LCA-related phosphatase
- PTPTY-28
- R-PTP-alpha
- protein tyrosine phosphatase alpha
- protein tyrosine phosphatase receptor type alpha
- protein-tyrosine-phosphatase alpha
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