PTP4A3 Products
(Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))
Categories
The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. [provided by RefSeq, Jul 2008].
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Featured PTP4A3 Categories
PTP4A3 Antibodies
High quality antibodies with extensive validation data.
PTP4A3 ELISA Kits
Reliable ELISA kits for a wide range of species.
PTP4A3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PTP4A3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (3)
Cat. No.
ABIN7435550
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, ICC, IF
Validations
- (3)
Cat. No.
ABIN6264515
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (3)
Cat. No.
ABIN1682391
Quantity
100 μg
Datasheet
Datasheet
Recommended PTP4A3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6958954
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4884249
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6384905
Quantity
96 tests
Datasheet
Datasheet
Recommended PTP4A3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
Cat. No.
ABIN7275479
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN666667
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316805
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PTP4A3 products
: "PRL-3 engages the focal adhesion pathway in triple-negative breast cancer cells to alter actin structure and substrate adhesion properties critical for cell migration and invasion." in: Cancer letters, Vol. 380, Issue 2, pp. 505-12, (2016) (PubMed).: "Loss of the oncogenic phosphatase PRL-3 promotes a TNF-R1 feedback loop that mediates triple-negative breast cancer growth." in: Oncogenesis, Vol. 5, Issue 8, pp. e255, (2016) (PubMed).
: "PRL-3 activates mTORC1 in Cancer Progression." in: Scientific reports, Vol. 5, pp. 17046, (2015) (PubMed).
: "8q24 amplification is associated with Myc expression and prostate cancer progression and is an independent predictor of recurrence after radical prostatectomy." in: Human pathology, Vol. 44, Issue 8, pp. 1617-23, (2013) (PubMed).
: "Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells." in: Blood, Vol. 111, Issue 2, pp. 806-15, (2008) (PubMed).
: "Structural insights into molecular function of the metastasis-associated phosphatase PRL-3." in: The Journal of biological chemistry, Vol. 279, Issue 12, pp. 11882-9, (2004) (PubMed).
: "Structure of human PRL-3, the phosphatase associated with cancer metastasis." in: FEBS letters, Vol. 565, Issue 1-3, pp. 181-7, (2004) (PubMed).
: "Phosphatase of regenerating liver-3 promotes motility and metastasis of mouse melanoma cells." in: The American journal of pathology, Vol. 164, Issue 6, pp. 2039-54, (2004) (PubMed).
: "High expression of PRL-3 promotes cancer cell motility and liver metastasis in human colorectal cancer: a predictive molecular marker of metachronous liver and lung metastases." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 21, pp. 7318-28, (2004) (PubMed).
: "PRL-3 expression in metastatic cancers." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 9, Issue 15, pp. 5607-15, (2003) (PubMed).
Synonyms and alternative names related to PTP4A3
protein tyrosine phosphatase type IVA, member 3 (PTP4A3), protein tyrosine phosphatase type IVA, member 3 (ptp4a3), protein tyrosine phosphatase type IVA, member 3 L homeolog (ptp4a3.L), protein tyrosine phosphatase 4a3 (Ptp4a3), protein tyrosine phosphatase type IVA, member 3 (Ptp4a3), AV088979, pPtp4a3, PRL-3, prl-3, Prl-3, PRL-R, PRL3, prl3, PTP4A3, ptpcaax3, wu:fc54b05, wu:fv52d11, zgc:77109Protein level used designations for PTP4A3
- potentially prenylated protein tyrosine phosphatase
- protein tyrosine phosphatase type IVA 3
- protein-tyrosine phosphatase 4a3
- protein-tyrosine phosphatase of regenerating liver 3
- PRL-3
- fc54b05
- fv52d11
- xPRL-3
- protein tyrosine phosphatase type IVA, member 3
- protein tyrosine phosphatase 4a3
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