PTK7 Products
(PTK7 Protein tyrosine Kinase 7 (PTK7))
Categories
This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012].
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Featured PTK7 Categories
PTK7 Antibodies
High quality antibodies with extensive validation data.
PTK7 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PTK7 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN392230
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN519485
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, FACS
Validations
- (4)
Cat. No.
ABIN1497127
Quantity
100 μL
Datasheet
Datasheet
Recommended PTK7 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6974488
Quantity
96 tests
Datasheet
Datasheet
Recommended PTK7 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274039
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274040
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7092672
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PTK7 products
: "PTK7 protein is decreased in epithelial ovarian carcinomas with poor prognosis." in: International journal of clinical and experimental pathology, Vol. 7, Issue 11, pp. 7881-9, (2014) (PubMed).: "Downstream signaling and genome-wide regulatory effects of PTK7 pseudokinase and its proteolytic fragments in cancer cells." in: Cell communication and signaling : CCS, Vol. 12, pp. 15, (2014) (PubMed).
: "Protein-tyrosine pseudokinase 7 (PTK7) directs cancer cell motility and metastasis." in: The Journal of biological chemistry, Vol. 289, Issue 35, pp. 24238-49, (2014) (PubMed).
: "A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma." in: Cancer research, Vol. 74, Issue 10, pp. 2892-902, (2014) (PubMed).
: "The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis." in: The Journal of biological chemistry, Vol. 285, Issue 46, pp. 35740-9, (2010) (PubMed).
: "Human CD4+ T cell recent thymic emigrants are identified by protein tyrosine kinase 7 and have reduced immune function." in: The Journal of experimental medicine, Vol. 206, Issue 2, pp. 275-85, (2009) (PubMed).
: "Soluble PTK7 inhibits tube formation, migration, and invasion of endothelial cells and angiogenesis." in: Biochemical and biophysical research communications, Vol. 371, Issue 4, pp. 793-8, (2008) (PubMed).
: "High-throughput analysis of genome-wide receptor tyrosine kinase expression in human cancers identifies potential novel drug targets." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 10, Issue 4, pp. 1241-9, (2004) (PubMed).
: "PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates." in: Nature, Vol. 430, Issue 6995, pp. 93-8, (2004) (PubMed).
: "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry." in: Nature biotechnology, Vol. 21, Issue 6, pp. 660-6, (2003) (PubMed).
Synonyms and alternative names related to PTK7
protein tyrosine kinase 7 (inactive) (PTK7), protein tyrosine kinase 7 (Ptk7), PTK7 protein tyrosine kinase 7 (Ptk7), 8430404F20Rik, CCK-4, CCK4, chz, KLG, mPTK7/CCK4, PTK7, SrfProtein level used designations for PTK7
- PTK7 protein tyrosine kinase 7
- inactive tyrosine-protein kinase 7
- tyrosine-protein kinase-like 7-like
- colon carcinoma kinase 4
- pseudo tyrosine kinase receptor 7
- tyrosine-protein kinase-like 7
- serum response factor
- protein chuzhoi
- protein-tyrosine kinase 7
- receptor tyrosine kinase-like protein
- kinase-like protein
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