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PTHLH Products

(Parathyroid Hormone-Like Hormone (PTHLH))

Categories

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone. [provided by RefSeq, Jul 2008].

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Featured PTHLH Categories

PTHLH Antibodies

High quality antibodies with extensive validation data.

Recommended PTHLH Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Chicken, Cow, Dog, Human
Application WB
Validations
  • (1)
Cat. No. ABIN7304601
Quantity 30 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, CA, DB, IA, ISt, WB
Validations
Cat. No. ABIN641289
Quantity 200 μg
Datasheet Datasheet
Reactivity Rainbow Trout
Application ELISA
Validations
Cat. No. ABIN2754021
Quantity 100 μg
Datasheet Datasheet

Recommended PTHLH Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7493656
Quantity 200 μg
Datasheet Datasheet
Reactivity Chicken
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7496041
Quantity 200 μg
Datasheet Datasheet

Latest Publications for our PTHLH products

Plas, Poland, Faber, Argilès, van Dijk, Laviano, Meijerink, Witkamp, van Helvoort, van Norren: "A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice." in: International journal of molecular sciences, Vol. 20, Issue 20, (2020) (PubMed).

Duan, Li, Tu, Xie, Li, Qi, Li: "Identification of a potential gene target for osteoarthritis based on bioinformatics analyses." in: Journal of orthopaedic surgery and research, Vol. 15, Issue 1, pp. 228, (2020) (PubMed).

Zhang, Cheng, Wang, Leung, Mak: "Hedgehog signaling in bone regulates whole-body energy metabolism through a bone-adipose endocrine relay mediated by PTHrP and adiponectin." in: Cell death and differentiation, Vol. 24, Issue 2, pp. 225-237, (2018) (PubMed).

Ghareghani, Scavo, Arnoult, Zibara, Farhadi: "Melatonin therapy reduces the risk of osteoporosis and normalizes bone formation in multiple sclerosis." in: Fundamental & clinical pharmacology, Vol. 32, Issue 2, pp. 181-187, (2018) (PubMed).

Macari, Sharma, Wyatt, da Silva, Dias, Silva, Szawka, Grattan: "Lactation induces increases in the RANK/RANKL/OPG system in maxillary bone." in: Bone, Vol. 110, pp. 160-169, (2018) (PubMed).

Teixeira, de Castro Raucci, Alonso, Coletta, Rosa, de Oliveira: "Osteopontin expression in co-cultures of human squamous cell carcinoma-derived cells and osteoblastic cells and its effects on the neoplastic cell phenotype and osteoclastic activation." in: Tumour biology, Vol. 37, Issue 9, pp. 12371-12385, (2016) (PubMed).

Hou, Wang, Liang, Zhang, Liu, Zhang, Zhang, Chen: "Animal and cellular models of hepatocellular carcinoma bone metastasis: establishment and characterisation." in: Journal of cancer research and clinical oncology, (2015) (PubMed).

Wu, Wang, Huang, Yang, Wu, Hou, Hsieh, Hsieh, Cheng, Hsu, Chang: "Cytoplasmic and nuclear parathyroid hormone-related proteins are opposing prognostic factors in patients with non-small-cell lung cancer who have undergone curative resection." in: Japanese journal of clinical oncology, Vol. 45, Issue 3, pp. 267-73, (2015) (PubMed).

Kim, Kim, Lee, Ma, Park, Chung: "15-deoxy-δ12,14-prostaglandin j2 inhibits osteolytic breast cancer bone metastasis and estrogen deficiency-induced bone loss." in: PLoS ONE, Vol. 10, Issue 4, pp. e0122764, (2015) (PubMed).

Clarke, Russell, Findlay, Sastra, Anderson, Skinner, Atkins, Zajac, Davey: "A ROLE FOR THE CALCITONIN RECEPTOR TO LIMIT BONE LOSS DURING LACTATION IN FEMALE MICE BY INHIBITING OSTEOCYTIC OSTEOLYSIS." in: Endocrinology, pp. en20151345, (2015) (PubMed).

Synonyms and alternative names related to PTHLH

parathyroid hormone like hormone (PTHLH), parathyroid hormone-like hormone (Pthlh), parathyroid hormone-like hormone a (pthlha), parathyroid hormone-like hormone L homeolog (pthlh.L), parathyroid hormone-like peptide (Pthlh), parathyroid hormone like hormone (Pthlh), parathyroid hormone 1 receptor (PTH1R), BDE2, HHM, PLP, PTH-like, PTHLH, pthlh, PTHR, PTHR1, PTHRP, PTHrP, pthrp, Pthrp, si:ch211-286m4.5

Protein level used designations for PTHLH

  • PTH-rP
  • PTH-related protein
  • osteostatin
  • parathyroid hormone-like related protein
  • parathyroid hormone-related protein
  • PTHrP
  • parathyroid hormone-like peptide
  • parathyroid hormone-like protein
  • parathyroid-like peptide
  • parathyroid hormone-like hormone
  • parathyroid hormone related protein
  • PLP
  • PTH-related peptide
  • parathyroid hormone-related peptide
  • Parathyroid hormone-related protein
  • PTH/PTHrP type I receptor
  • parathyroid hormone receptor 1
  • parathyroid hormone/parathyroid hormone-related peptide receptor
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