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PTH1R Products

(Parathyroid Hormone 1 Receptor (PTH1R))
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010].

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Featured PTH1R Categories

PTH1R Antibodies

High quality antibodies with extensive validation data.

PTH1R ELISA Kits

Reliable ELISA kits for a wide range of species.

PTH1R Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PTH1R Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6257431
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, ICC
Validations
  • (2)
  • (3)
Cat. No. ABIN969372
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7189439
Quantity 100 μg
Datasheet Datasheet

Recommended PTH1R ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969151
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958402
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884292
Quantity 96 tests
Datasheet Datasheet

Recommended PTH1R Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316771
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN4371263
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN7318865
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our PTH1R products

Kang, Lim, Noh, Park, Cho, Susztak, Jung: "Effective reconstruction of functional organotypic kidney spheroid for in vitro nephrotoxicity studies." in: Scientific reports, Vol. 9, Issue 1, pp. 17610, (2019) (PubMed).

Ma, Wu, Jin: "The association between parathyroid hormone 1‑34 and the Wnt/β‑catenin signaling pathway in a rat model of osteoarthritis." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8799-8807, (2018) (PubMed).

Kadmiel, Matson, Espenschied, Lenhart, Caron: "Loss of receptor activity-modifying protein 2 in mice causes placental dysfunction and alters PTH1R regulation." in: PLoS ONE, Vol. 12, Issue 7, pp. e0181597, (2017) (PubMed).

Wang, Wang, Dai, Chen, Yang, Dai, Ou, Wang, Lin: "Effects of Intermittent Administration of Parathyroid Hormone (1-34) on Bone Differentiation in Stromal Precursor Antigen-1 Positive Human Periodontal Ligament Stem Cells." in: Stem cells international, Vol. 2016, pp. 4027542, (2016) (PubMed).

Li, He, Yao, Song, Zeng, Peng, Rosol, Deng: "TGF-? Induces Degradation of PTHrP Through Ubiquitin-Proteasome System in Hepatocellular Carcinoma." in: Journal of Cancer, Vol. 6, Issue 6, pp. 511-8, (2015) (PubMed).

Madiraju, Gawri, Wang, Antoniou, Mwale: "Mechanism of parathyroid hormone-mediated suppression of calcification markers in human intervertebral disc cells." in: European cells & materials, Vol. 25, pp. 268-83, (2013) (PubMed).

Wang, Yang, Friedman: "Na/H exchange regulatory factor 1, a novel AKT-associating protein, regulates extracellular signal-regulated kinase signaling through a B-Raf-mediated pathway." in: Molecular biology of the cell, Vol. 19, Issue 4, pp. 1637-45, (2008) (PubMed).

Dean, Vilardaga, Potts, Gardella: "Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor." in: Molecular endocrinology (Baltimore, Md.), Vol. 22, Issue 1, pp. 156-66, (2007) (PubMed).

Yang, Hoang, Kubo, Kawano, Chou, Sowers, Huvos, Meyers, Healey, Gorlick: "Over-expression of parathyroid hormone Type 1 receptor confers an aggressive phenotype in osteosarcoma." in: International journal of cancer. Journal international du cancer, Vol. 121, Issue 5, pp. 943-54, (2007) (PubMed).

Synonyms and alternative names related to PTH1R

parathyroid hormone 1 receptor (PTH1R), parathyroid hormone 1 receptor (Pth1r), parathyroid hormone 1 receptor a (pth1ra), PFE, PPR, PTH, PTH1, PTHR, Pthr, PTHR1, Pthr1, pthr1, PTHrel, zPTH1R

Protein level used designations for PTH1R

  • PTH/PTHr receptor
  • PTH/PTHrP type I receptor
  • PTH1 receptor
  • parathyroid hormone receptor 1
  • parathyroid hormone/parathyroid hormone-related peptide receptor
  • parathyroid hormone/parathyroid hormone-related protein receptor
  • seven transmembrane helix receptor
  • PTH-related peptide receptor
  • PTH/PTHrP receptor
  • parathyroid hormone 1 receptor
  • parathyroid hormone/parathyroid hormone-related peptide receptor-like
  • parathyroid hormone receptor-1
  • parathyroid receptor
  • LOW QUALITY PROTEIN: parathyroid hormone/parathyroid hormone-related peptide receptor
  • Parathyroid hormone/parathyroid hormone-related peptide receptor
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