PTGIS Products
(Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008].
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Featured PTGIS Categories
PTGIS Antibodies
High quality antibodies with extensive validation data.
PTGIS ELISA Kits
Reliable ELISA kits for a wide range of species.
PTGIS Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PTGIS Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, ICC, IF
Validations
- (3)
Cat. No.
ABIN6259069
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
- (2)
Cat. No.
ABIN562513
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN519453
Quantity
100 μg
Datasheet
Datasheet
Recommended PTGIS ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6958871
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969666
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969667
Quantity
96 tests
Datasheet
Datasheet
Recommended PTGIS Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316752
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316750
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7391885
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PTGIS products
: "Grape Seed Procyanidin Extract Mediates Antineoplastic Effects against Lung Cancer via Modulations of Prostacyclin and 15-HETE Eicosanoid Pathways." in: Cancer prevention research (Philadelphia, Pa.), Vol. 9, Issue 12, pp. 925-932, (2016) (PubMed).: "Mechanism of prostacyclin-induced potentiation of glucose-induced insulin secretion." in: Endocrinology, Vol. 153, Issue 6, pp. 2612-22, (2012) (PubMed).
Synonyms and alternative names related to PTGIS
prostaglandin I2 synthase (PTGIS), prostaglandin I2 (prostacyclin) synthase (Ptgis), prostaglandin I2 (prostacyclin) synthase (ptgis), prostacyclin synthase (VDBG_06319), prostaglandin I2 synthase (Ptgis), CYP8, Cyp8, CYP8A1, Cyp8a1, PGIS, Pgis, PTGI, PTGIS, ptgislProtein level used designations for PTGIS
- cytochrome P450, family 8, subfamily A, polypeptide 1
- prostacyclin synthase
- prostaglandin I2 synthase
- prostaglandin I2 (prostacyclin) synthase like
- prostaglandin I2 (prostacyclin) synthase
- cytochrome P450 8A1
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