PTGER4 Products
(Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4))
Categories
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008].
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Featured PTGER4 Categories
PTGER4 Antibodies
High quality antibodies with extensive validation data.
PTGER4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PTGER4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Bat, Cow, Dog, Hamster, Horse, Human, Monkey, Mouse, Rat
Application
IHC (p), IHC, ICC
Validations
- (5)
Cat. No.
ABIN1049258
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
IHC (p), IHC, ICC
Validations
- (5)
Cat. No.
ABIN1049257
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6259076
Quantity
100 μL
Datasheet
Datasheet
Recommended PTGER4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7491721
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316734
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316732
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PTGER4 products
: "Restoration of the type I IFN-IL-1 balance through targeted blockade of PTGER4 inhibits autoimmunity in NOD mice." in: JCI insight, Vol. 3, Issue 3, (2018) (PubMed).: "Microsomal Prostaglandin E Synthase-1 Facilitates an Intercellular Interaction between CD4⁺ T Cells through IL-1β Autocrine Function in Experimental Autoimmune Encephalomyelitis." in: International journal of molecular sciences, Vol. 18, Issue 12, (2018) (PubMed).
: "GW627368X inhibits proliferation and induces apoptosis in cervical cancer by interfering with EP4/EGFR interactive signaling." in: Cell death & disease, Vol. 7, pp. e2154, (2016) (PubMed).
: "Comprehensive Profiling of GPCR Expression in Ghrelin-Producing Cells." in: Endocrinology, Vol. 157, Issue 2, pp. 692-704, (2016) (PubMed).
: "The expression of prostaglandin-E2 and its receptor in the oviduct of Chinese brown frog (Rana dybowskii)." in: Prostaglandins & other lipid mediators, Vol. 124, pp. 9-15, (2016) (PubMed).
: "Molecular inhibition of prostaglandin E2 with GW627368X: Therapeutic potential and preclinical safety assessment in mouse sarcoma model." in: Cancer biology & therapy, Vol. 16, Issue 6, pp. 922-32, (2015) (PubMed).
: "Cell entry of bovine ephemeral fever virus requires activation of Src-JNK-AP1 and PI3K-Akt-NF-κB pathways as well as Cox-2-mediated PGE2 /EP receptor signalling to enhance clathrin-mediated virus ..." in: Cellular microbiology, Vol. 17, Issue 7, pp. 967-87, (2015) (PubMed).
: "Inactivation of PI3-K/Akt and reduction of SP1 and p65 expression increase the effect of solamargine on suppressing EP4 expression in human lung cancer cells." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 154, (2015) (PubMed).
: "Chemo-sensitizing effects of EP4 receptor-induced inactivation of nuclear factor-κB." in: European journal of pharmacology, Vol. 742, pp. 81-8, (2014) (PubMed).
: "Prostaglandin E receptor EP4 is a therapeutic target in breast cancer cells with stem-like properties." in: Breast cancer research and treatment, Vol. 143, Issue 1, pp. 19-31, (2014) (PubMed).
Synonyms and alternative names related to PTGER4
prostaglandin E receptor 4 (PTGER4), prostaglandin E receptor 4 (subtype EP4) (PTGER4), prostaglandin E receptor 4 (subtype EP4) a (ptger4a), prostaglandin E receptor 4 (ptger4), prostaglandin E receptor 4 subtype EP4 (ptger4), prostaglandin E receptor 4 (subtype EP4) (Ptger4), prostaglandin E receptor 4 (Ptger4), EP4, ep4, EP4R, PGE2R-EP4, Ptger, ptger4, PTGER4, ptger4l, Ptgerep4Protein level used designations for PTGER4
- prostaglandin E receptor 4, subtype EP4
- prostaglandin E2 receptor EP4 subtype
- prostaglandin E2 receptor subtype 4
- prostaglandin E receptor 4 (subtype EP4)
- ep4
- ep4a
- prostaglandin E receptor 4
- prostaglandin E receptor 4 subtype EP4
- PGE receptor EP4 subtype
- PGE receptor, EP4 subtype
- PGE2 receptor EP4 subtype
- prostanoid EP4 receptor
- prostaglandin E receptor 4 (EP4 subtype)
- prostaglandin E receptor EP4 subtype
- prostaglandin E2 receptor type 4
- PGE receptor, subtype EP4
- prostaglandin receptor EP4 subtype
- prostaglandin E2 subtype EP4 receptor
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