PTGDS Products
(Prostaglandin D2 Synthase (PTGDS))
Categories
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008].
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Featured PTGDS Categories
PTGDS Antibodies
High quality antibodies with extensive validation data.
PTGDS ELISA Kits
Reliable ELISA kits for a wide range of species.
PTGDS Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PTGDS Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7432472
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (2)
Cat. No.
ABIN7426007
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA, IF
Validations
- (2)
Cat. No.
ABIN7164874
Quantity
100 μg
Datasheet
Datasheet
Recommended PTGDS ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
Cat. No.
ABIN6574195
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969645
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969244
Quantity
96 tests
Datasheet
Datasheet
Recommended PTGDS Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124606
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314800
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316723
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PTGDS products
: "Determination of neuroinflammatory biomarkers in autistic and neurotypical Saudi children." in: Metabolic brain disease, Vol. 34, Issue 4, pp. 1049-1060, (2020) (PubMed).: "Prostaglandin D2 synthase/GPR44: a signaling axis in PNS myelination." in: Nature neuroscience, Vol. 17, Issue 12, pp. 1682-92, (2014) (PubMed).
: "18F-glutathione conjugate as a PET tracer for imaging tumors that overexpress L-PGDS enzyme." in: PLoS ONE, Vol. 9, Issue 8, pp. e104118, (2014) (PubMed).
: "Lipocalin-type prostaglandin D synthase is associated with coronary vasospasm and vasomotor reactivity in response to acetylcholine." in: Circulation journal : official journal of the Japanese Circulation Society, Vol. 75, Issue 4, pp. 897-904, (2011) (PubMed).
: "Lipocalin-type prostaglandin D synthase as a regulator of the retinoic acid signalling in melanocytes." in: Journal of biochemistry, Vol. 148, Issue 2, pp. 139-48, (2010) (PubMed).
: "Decreased intrathecal synthesis of prostaglandin D2 synthase in the cerebrospinal fluid of patients with acute inflammatory demyelinating polyneuropathy." in: Journal of neuroimmunology, Vol. 206, Issue 1-2, pp. 100-5, (2009) (PubMed).
: "7beta-Hydroxy-epiandrosterone-mediated regulation of the prostaglandin synthesis pathway in human peripheral blood monocytes." in: Steroids, Vol. 73, Issue 11, pp. 1148-59, (2008) (PubMed).
: "An aberrant protein complex in CSF as a biomarker of Alzheimer disease." in: Neurology, Vol. 70, Issue 23, pp. 2212-8, (2008) (PubMed).
: "Lipocalin-type prostaglandin D synthase/beta-trace is a major amyloid beta-chaperone in human cerebrospinal fluid." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 15, pp. 6412-7, (2007) (PubMed).
Synonyms and alternative names related to PTGDS
phosphogluconate dehydrogenase (PGD), hematopoietic prostaglandin D synthase (HPGDS), prostaglandin D2 synthase (PTGDS), hematopoietic prostaglandin D synthase (Hpgds), prostaglandin D2 synthase (brain) (Ptgds), prostaglandin D2 synthase (Ptgds), prostaglandin D synthase (LOC100009453), prostaglandin D2 synthase 21kDa (brain) (PTGDS), 6PGD, 21kDa, GSTS, GSTS1-1, H-PGDS, L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2, PH2DISO, Ptgds2, Ptgs3Protein level used designations for PTGDS
- 6-phosphogluconate dehydrogenase, decarboxylating
- GST class-sigma
- glutathione S-transferase sigma
- glutathione-dependent PGD synthase
- glutathione-dependent PGD synthetase
- glutathione-requiring prostaglandin D synthase
- hematopoietic prostaglandin D2 synthase
- prostaglandin-H2 D-isomerase
- PGD2 synthase
- beta-trace protein
- cerebrin-28
- glutathione-independent PGD synthase
- glutathione-independent PGD synthetase
- lipocalin-type prostaglandin D synthase
- lipocalin-type prostaglandin-D synthase
- prostaglandin D synthase
- prostaglandin-D2 synthase
- glutathione S-transferase
- prostaglandin D2 synthase 2, hematopoietic
- H-PGDS
- prostaglandin-D synthase
- prostaglandin D2 synthase (21 kDa, brain)
- PGDS
- PGDS2
- Prostaglandin D synthase
- prostaglandin D2 synthase 21kDa (brain)
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