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PTBP2 Products

(Polypyrimidine Tract Binding Protein 2 (PTBP2))

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The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein but it is expressed primarily in the brain. [provided by RefSeq, Jul 2008].

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Featured PTBP2 Categories

PTBP2 Antibodies

High quality antibodies with extensive validation data.

PTBP2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PTBP2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (6)
Cat. No. ABIN6146373
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7269465
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (3)
Cat. No. ABIN566178
Quantity 100 μg
Datasheet Datasheet

Recommended PTBP2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6206361
Quantity 96 tests
Datasheet Datasheet

Recommended PTBP2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316694
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316696
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3086617
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PTBP2 products

Yip, Fuhlbrigge, Taylor, Creusot, Nishikawa-Matsumura, Whiting, Schartner, Akter, von Herrath, Fathman: "Inflammation and hyperglycemia mediate Deaf1 splicing in the pancreatic lymph nodes via distinct pathways during type 1 diabetes." in: Diabetes, Vol. 64, Issue 2, pp. 604-17, (2015) (PubMed).

Liang, Lin, Lin, Lin: "The impact of RNA binding motif protein 4-regulated splicing cascade on the progression and metabolism of colorectal cancer cells." in: Oncotarget, Vol. 6, Issue 35, pp. 38046-60, (2015) (PubMed).

Shibasaki, Tokunaga, Sakamoto, Sagara, Noguchi, Sasaoka, Yoshida: "PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus." in: Cerebral cortex (New York, N.Y. : 1991), Vol. 23, Issue 8, pp. 1824-35, (2013) (PubMed).

Xu, Hecht: "Polypyrimidine tract-binding protein 2 binds to selective, intronic messenger RNA and microRNA targets in the mouse testis." in: Biology of reproduction, Vol. 84, Issue 3, pp. 435-9, (2011) (PubMed).

Suckale, Wendling, Masjkur, Jäger, Münster, Anastassiadis, Stewart, Solimena: "PTBP1 is required for embryonic development before gastrulation." in: PLoS ONE, Vol. 6, Issue 2, pp. e16992, (2011) (PubMed).

Xue, Zhou, Wu, Zhu, Ji, Kwon, Zhang, Yeo, Black, Sun, Fu, Zhang: "Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping." in: Molecular cell, Vol. 36, Issue 6, pp. 996-1006, (2010) (PubMed).

Sasabe, Futai, Ishiura: "Polypyrimidine tract-binding protein 1 regulates the alternative splicing of dopamine receptor D2." in: Journal of neurochemistry, Vol. 116, Issue 1, pp. 76-81, (2010) (PubMed).

Resnick, Segall, G, Lupowitz, Zisapel: "Alternative splicing of neurexins: a role for neuronal polypyrimidine tract binding protein." in: Neuroscience letters, Vol. 439, Issue 3, pp. 235-40, (2008) (PubMed).

Rolland, Evrard, Guitton, Lavigne, Calvel, Couvet, Jégou, Pineau: "Two-dimensional fluorescence difference gel electrophoresis analysis of spermatogenesis in the rat." in: Journal of proteome research, Vol. 6, Issue 2, pp. 683-97, (2007) (PubMed).

Boutz, Stoilov, Li, Lin, Chawla, Ostrow, Shiue, Ares, Black: "A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons." in: Genes & development, Vol. 21, Issue 13, pp. 1636-52, (2007) (PubMed).

Synonyms and alternative names related to PTBP2

polypyrimidine tract binding protein 2 (PTBP2), polypyrimidine tract binding protein 2 (Ptbp2), polypyrimidine tract binding protein 2b (ptbp2b), polypyrimidine tract binding protein 2a (ptbp2a), brPTB, im:7153495, nPTB, nPTB5, nPTB6, nPTB7, nPTB8, PTB, Ptb2, PTBLP, PTBP2, ptbp2, si:ch211-160l17.2, wu:fa08f05, wu:fc05d10, zgc:113074

Protein level used designations for PTBP2

  • PTB-like protein
  • neural polypyrimidine tract binding protein
  • neural polypyrimidine tract-binding protein
  • neurally-enriched homolog of PTB
  • polypyrimidine tract-binding protein 2
  • splicing regulator
  • RRM-type RNA-binding protein brPTB
  • brain-enriched PTB
  • brain-enriched polypyrimidine tract-binding protein
  • polypyrimidine tract binding protein 2
  • polypyrimidine tract-binding protein 2-like
  • uncharacterized protein LOC541437
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