PSMD8 Products
(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 8 (PSMD8))
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008].
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Featured PSMD8 Categories
PSMD8 Antibodies
High quality antibodies with extensive validation data.
PSMD8 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PSMD8 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (9)
Cat. No.
ABIN7075226
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7142221
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
IHC, IF
Validations
- (2)
Cat. No.
ABIN7262875
Quantity
200 μL
Datasheet
Datasheet
Recommended PSMD8 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316655
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316657
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7425086
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PSMD8 products
: "Grsf1-induced translation of the SNARE protein Use1 is required for expansion of the erythroid compartment." in: PLoS ONE, Vol. 9, Issue 9, pp. e104631, (2014) (PubMed).: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).
: "Nob1p, a new essential protein, associates with the 26S proteasome of growing saccharomyces cerevisiae cells." in: Gene, Vol. 243, Issue 1-2, pp. 37-45, (2000) (PubMed).
: "Genetic evidence for interaction between components of the yeast 26S proteasome: combination of a mutation in RPN12 (a lid component gene) with mutations in RPT1 (an ATPase gene) causes synthetic ..." in: Molecular & general genetics : MGG, Vol. 262, Issue 1, pp. 145-53, (1999) (PubMed).
: "The ubiquitin system." in: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).
Synonyms and alternative names related to PSMD8
proteasome 26S subunit, non-ATPase 8 (PSMD8), proteasome 26S subunit, non-ATPase 8 S homeolog (psmd8.S), proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 (Psmd8), proteasome 26S subunit, non-ATPase 8 (Psmd8), proteasome 26S subunit, non-ATPase 8 L homeolog (psmd8.L), proteasome 26S subunit, non-ATPase 8 (psmd8), proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 pseudogene (LOC468490), 6720456J22Rik, AA407360, AL033291, AL033322, AL033323, C76433, fa93g07, fb17c09, fb49a10, HIP6, hip6, HYPF, hypf, Nin1p, nin1p, p31, psmd8, PSMD8, psmd8a, psmd8b, Rpn12, rpn12, S14, wu:fa93g07, wu:fb17c09, wu:fb49a10, zgc:86762Protein level used designations for PSMD8
- 26S proteasome non-ATPase regulatory subunit 8
- 26S proteasome regulatory subunit RPN12
- 26S proteasome regulatory subunit S14
- 26S proteasome regulatory subunit p31
- proteasome 26S non-ATPase subunit 8 b
- proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 b
- proteasome 26S non-ATPase subunit 8
- proteasome 26S subunit, non-ATPase, 8
- proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 a
- proteasome 26S non-ATPase subunit 8 a
- proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
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