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PSMD3 Products

(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 3 (PSMD3))

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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count. [provided by RefSeq, Jul 2012].

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Featured PSMD3 Categories

PSMD3 Antibodies

High quality antibodies with extensive validation data.

PSMD3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PSMD3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, FACS
Validations
  • (5)
Cat. No. ABIN1499980
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (4)
Cat. No. ABIN6243826
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
Cat. No. ABIN7130740
Quantity 100 μL
Datasheet Datasheet

Recommended PSMD3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6230499
Quantity 96 tests
Datasheet Datasheet

Recommended PSMD3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1316635
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316637
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3086737
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PSMD3 products

Gerhardt, Lier, Burmühl, Struchtrup, Deutschmann, Vetter, Leu, Reeg, Grune, Rüther: "The transition zone protein Rpgrip1l regulates proteasomal activity at the primary cilium." in: The Journal of cell biology, Vol. 210, Issue 1, pp. 115-33, (2015) (PubMed).

Wei, Williams, Dang, Darden, Betz, Humble, Chang, Trempus, Johnson, Cannon, Tennant: "Identification of a specific motif of the DSS1 protein required for proteasome interaction and p53 protein degradation." in: Journal of molecular biology, Vol. 383, Issue 3, pp. 693-712, (2008) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Claas, Wahl, Orlicky, Karaduman, Schnölzer, Kempf, Zöller: "The tetraspanin D6.1A and its molecular partners on rat carcinoma cells." in: The Biochemical journal, Vol. 389, Issue Pt 1, pp. 99-110, (2005) (PubMed).

Isono, Saeki, Yokosawa, Toh-e: "Rpn7 Is required for the structural integrity of the 26 S proteasome of Saccharomyces cerevisiae." in: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27168-76, (2004) (PubMed).

Terada, Baracskay, Kinter, Melrose, Brophy, Boucheix, Bjartmar, Kidd, Trapp: "The tetraspanin protein, CD9, is expressed by progenitor cells committed to oligodendrogenesis and is linked to beta1 integrin, CD81, and Tspan-2." in: Glia, Vol. 40, Issue 3, pp. 350-9, (2002) (PubMed).

Park, Yashiro, Tai, Toyo-oka, Hamaoka, Yagita, Okumura, Neben, Fujiwara: "Differential involvement of a Fas-CPP32-like protease pathway in apoptosis of TCR/CD9-costimulated, naive T cells and TCR-restimulated, activated T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 12, pp. 5790-6, (1998) (PubMed).

Glickman, Rubin, Coux, Wefes, Pfeifer, Cjeka, Baumeister, Fried, Finley: "A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3." in: Cell, Vol. 94, Issue 5, pp. 615-23, (1998) (PubMed).

Finley, Tanaka, Mann, Feldmann, Hochstrasser, Vierstra, Johnston, Hampton, Haber, Mccusker, Silver, Frontali, Thorsness, Varshavsky, Byers, Madura, Reed, Wolf, Jentsch, Sommer, Baumeister, Goldberg et al.: "Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. ..." in: Trends in biochemical sciences, Vol. 23, Issue 7, pp. 244-5, (1998) (PubMed).

Hershko, Ciechanover: "The ubiquitin system." in: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).

Synonyms and alternative names related to PSMD3

proteasome 26S subunit, non-ATPase 3 (PSMD3), proteasome 26S subunit, non-ATPase 3 S homeolog (psmd3.S), proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 (Psmd3), proteasome 26S subunit, non-ATPase 3 (Psmd3), 26S proteasome non-ATPase regulatory subunit 3 (rpn-3), AI255837, AntP91a, D11Bwg1349e, P58, Psd3, RPN3, S3, TSTA2, Tstap91a

Protein level used designations for PSMD3

  • 26S proteasome non-ATPase regulatory subunit 3
  • 26S proteasome regulatory subunit RPN3
  • 26S proteasome regulatory subunit S3
  • proteasome subunit p58
  • tissue specific transplantation antigen 2
  • tissue specific transplantation antigen P91A
  • transplantation antigen P91A
  • tum-P91A antigen
  • proteasome 26S non-ATPase subunit 3
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