PSMD12 Products
(Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))
Categories
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. [provided by RefSeq, Jul 2008].
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Featured PSMD12 Categories
PSMD12 Antibodies
High quality antibodies with extensive validation data.
PSMD12 ELISA Kits
Reliable ELISA kits for a wide range of species.
PSMD12 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PSMD12 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (3)
Cat. No.
ABIN6257738
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7246631
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7142206
Quantity
100 μL
Datasheet
Datasheet
Recommended PSMD12 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Chicken
Analytical Method
Validations
Cat. No.
ABIN1773467
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Sheep
Analytical Method
Validations
Cat. No.
ABIN1774691
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Goat
Analytical Method
Validations
Cat. No.
ABIN1749892
Quantity
96 tests
Datasheet
Datasheet
Recommended PSMD12 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316625
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316627
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Saccharomyces cerevisiae
Source
Yeast
Validations
Cat. No.
ABIN1618817
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PSMD12 products
: "Endoplasmic Reticulum-associated Degradation of Pca1p, a Polytopic Protein, via Interaction with the Proteasome at the Membrane." in: The Journal of biological chemistry, Vol. 291, Issue 29, pp. 15082-92, (2016) (PubMed).: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
: "The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome." in: Molecular biology of the cell, Vol. 18, Issue 2, pp. 569-80, (2007) (PubMed).
: "Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets." in: Nature genetics, Vol. 38, Issue 3, pp. 285-93, (2006) (PubMed).
: "Mammalian Cdh1/Fzr mediates its own degradation." in: The EMBO journal, Vol. 23, Issue 7, pp. 1619-26, (2004) (PubMed).
: "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. ..." in: Nature cell biology, Vol. 6, Issue 2, pp. 97-105, (2004) (PubMed).
: "Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. ..." in: Trends in biochemical sciences, Vol. 23, Issue 7, pp. 244-5, (1998) (PubMed).
: "The ubiquitin system." in: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).
Synonyms and alternative names related to PSMD12
proteasome 26S subunit, non-ATPase 12 (psmd12), proteasome 26S subunit, non-ATPase 12 (PSMD12), proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 (Psmd12), proteasome 26S subunit, non-ATPase 12 (Psmd12), 1500002F15Rik, AI480719, p55, P55, PSMD12, rpn5, Rpn5, wu:fb38a06, wu:fc34f08, wu:fc49f02Protein level used designations for PSMD12
- 26S proteasome non-ATPase regulatory subunit 12
- fc34f08
- proteasome 26S non-ATPase subunit 12
- proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
- 26S proteasome regulatory subunit RPN5
- 26S proteasome regulatory subunit p55
- 26S proteasome non-ATPase regulatory subunit 12-like
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