PSMC4 Products
(Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4))
Categories
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012].
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Featured PSMC4 Categories
PSMC4 Antibodies
High quality antibodies with extensive validation data.
PSMC4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PSMC4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7442066
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (6)
Cat. No.
ABIN562488
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7142234
Quantity
100 μg
Datasheet
Datasheet
Recommended PSMC4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316605
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7414021
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3086583
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PSMC4 products
: "Chaperone-mediated 26S proteasome remodeling facilitates free K63 ubiquitin chain production and aggresome clearance." in: The Journal of biological chemistry, Vol. 290, Issue 15, pp. 9455-64, (2015) (PubMed).: "Genetic background alters the severity and onset of neuromuscular disease caused by the loss of ubiquitin-specific protease 14 (usp14)." in: PLoS ONE, Vol. 8, Issue 12, pp. e84042, (2013) (PubMed).
: "Differential expression of novel tyrosine kinase substrates during breast cancer development." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 12, pp. 2072-87, (2007) (PubMed).
Synonyms and alternative names related to PSMC4
26S protease regulatory subunit 6B (LOC732870), regulatory particle, ATPase-like-3 (rpt-3), 26S protease regulatory subunit 6B (ATEG_04674), 26S protease regulatory subunit 6B (LELG_01296), 26S protease regulatory subunit 6B (HCAG_00039), 26S proteasome regulatory subunit 6B (LOC5568998), 26S protease regulatory subunit 6B (GL50803_7950), 26S protease regulatory subunit 6B (EDI_044950), 26S protease regulatory subunit 6B (AOR_1_1218154), 26S protease regulatory subunit 6B (PTRG_03339), 26S protease regulatory subunit 6B (psmC4), 26S protease regulatory subunit 6B (prs6b), 26S protease regulatory subunit 6B (LOC100381342), proteasome 26S subunit, ATPase 4 (psmc4), proteasome 26S subunit, ATPase 4 (PSMC4), proteasome (prosome, macropain) 26S subunit, ATPase, 4 (Psmc4), proteasome 26S subunit, ATPase 4 (Psmc4), AO090003000692, CIP21, DDBDRAFT_0188209, DDBDRAFT_0191435, DDB_0188209, DDB_0191435, MIP224, NCU02260.1, RPT3, S6, TBP-7, TBP7, Tbp7Protein level used designations for PSMC4
- 26S protease regulatory subunit 6B
- 26S protease regulatory subunit 6b
- 26S proteasome subunit ATPase 4
- HIV TAT binding-protein-related
- 26S proteasome regulatory complex ATPase RPT3
- GRMZM2G090904
- 26S proteasome AAA-ATPase subunit RPT3
- MB67-interacting protein
- Tat-binding protein 7
- protease 26S subunit 6
- CAR interacing protein 21
- CAR interacting protein 21
- TAT-binding protein 7
- TBP-7
- proteasome 26S ATPase subunit 4
- proteasome 26S subunit ATPase 4
- S6 ATPase
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