PSMC3 Products
(Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3 (PSMC3))
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. [provided by RefSeq, Jul 2008].
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Featured PSMC3 Categories
PSMC3 Antibodies
High quality antibodies with extensive validation data.
PSMC3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PSMC3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (9)
Cat. No.
ABIN5542634
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Dog, Human, Monkey, Rat
Application
WB, IHC, IF, IHC (p)
Validations
- (10)
Cat. No.
ABIN1501335
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (7)
Cat. No.
ABIN3022705
Quantity
100 μL
Datasheet
Datasheet
Recommended PSMC3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316603
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316601
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7414015
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our PSMC3 products
: "Genetic background alters the severity and onset of neuromuscular disease caused by the loss of ubiquitin-specific protease 14 (usp14)." in: PLoS ONE, Vol. 8, Issue 12, pp. e84042, (2013) (PubMed).: "Post-translationally modified S12, absent in transformed breast epithelial cells, is not associated with the 26S proteasome and is induced by proteasome inhibitor." in: International journal of cancer. Journal international du cancer, Vol. 111, Issue 3, pp. 338-47, (2004) (PubMed).
Synonyms and alternative names related to PSMC3
proteasome 26S subunit, ATPase 3 (PSMC3), proteasome (prosome, macropain) 26S subunit, ATPase 3 (Psmc3), proteasome 26S subunit, ATPase 3 (Psmc3), 26S protease regulatory subunit 6A (HCAG_00069), 26S protease regulatory subunit 6A (GL50803_4365), 26S protease regulatory subunit 6A (EDI_316920), 26S protease regulatory subunit 6a (CpipJ_CPIJ006888), 26S protease regulatory subunit 6a (CpipJ_CPIJ006889), 26S protease regulatory subunit 6a (CpipJ_CPIJ010864), 26S protease regulatory subunit 6A (prs6a), proteasome 26S subunit, ATPase 3 (psmc3), 26S protease regulatory subunit 6A-B (LOC100115023), 26S protease regulatory subunit 6A (BBOV_IV004580), 26S protease regulatory subunit 6A, putative (CGB_M2140W), 26S protease regulatory subunit 6A (psmC3), 26S protease regulatory subunit 6A-B (LOC100637883), proteasome 26S subunit, ATPase 3 S homeolog (psmc3.S), nth-like DNA glycosylase 1 S homeolog (nthl1.S), 23.m06430, DDBDRAFT_0186002, DDBDRAFT_0232967, DDB_0186002, DDB_0232967, MGC89608, NV15940, psmc3, PSMC3, psmc3-a, psmc3-b, TBP-1, TBP1, tbp10, wu:fb39a02, zgc:86713Protein level used designations for PSMC3
- 26S protease regulatory subunit 6A
- 26S proteasome AAA-ATPase subunit RPT5
- TBP-1
- Tat-binding protein 1
- human immunodeficiency virus tat transactivator binding protein-1
- proteasome 26S subunit ATPase 3
- proteasome subunit P50
- TAT-binding protein 1
- Tat binding protein 1
- spermatogenic cell/sperm-associated TAT-binding protein homolog SATA
- 26S protease regulatory subunit 6a
- proteasome (prosome, macropain) 26S subunit, ATPase, 3
- proteasome 26S ATPase subunit 3
- 26S protease regulatory subunit 6A-like
- 26S proteasome ATPase 3 subunit
- 26S protease regulatory subunit 6A-B
- 26S proteasome AAA-ATPase subunit RPT5-B
- TAT-binding protein 10
- TBP-10
- proteasome 26S subunit ATPase 3-B
- 26S protease regulatory subunit 6A-A
- 26S proteasome AAA-ATPase subunit RPT5-A
- TAT-binding protein 6
- TBP-6
- proteasome (prosome, macropain) 26S subunit, ATPase 3
- proteasome 26S subunit ATPase 3-A
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