PSMC2 Products
(Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 2 (PSMC2))
Categories
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2011].
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Featured PSMC2 Categories
PSMC2 Antibodies
High quality antibodies with extensive validation data.
PSMC2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended PSMC2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB
Validations
- (7)
Cat. No.
ABIN3015801
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7442063
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (4)
Cat. No.
ABIN7260033
Quantity
200 μL
Datasheet
Datasheet
Recommended PSMC2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6229788
Quantity
96 tests
Datasheet
Datasheet
Recommended PSMC2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316599
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7414018
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3011328
Quantity
100 μg
Datasheet
Datasheet
Synonyms and alternative names related to PSMC2
proteasome 26S subunit, ATPase 2 L homeolog (psmc2.L), proteasome (prosome, macropain) 26S subunit, ATPase 2 (psmc2), 26S protease regulatory subunit 7 (psmC2), proteasome 26S subunit, ATPase 2 (PSMC2), regulatory particle, ATPase-like-1 (rpt-1), 26S protease regulatory subunit 7 (GL50803_21331), 26S protease regulatory subunit 7 (EHI_080890), 26S protease regulatory subunit 7 (UREG_01412), 26S protease regulatory subunit 7 (PITG_10169), proteasome 26S subunit, ATPase 2 (Psmc2), 26S protease regulatory subunit 7 (GL50803_86683), 26S protease regulatory subunit 7 (Tsp_09237), proteasome (prosome, macropain) 26S subunit, ATPase 2 (Psmc2), proteasome 26S subunit, ATPase 2 (psmc2), DDBDRAFT_0168337, DDBDRAFT_0232966, DDB_0168337, DDB_0232966, MSS1, Nbla10058, NCU02840.1, psmc2, S7, xMSS1, zgc:63995Protein level used designations for PSMC2
- 26S protease regulatory subunit 7
- 26S proteasome AAA-ATPase subunit RPT1
- proteasome 26S subunit ATPase 2
- 26S proteasome ATPase 2 subunit
- mammalian suppressor of sgv-1 of yeast
- protease 26S subunit 7
- proteasome 26S subunit, ATPase, 2
- putative protein product of Nbla10058
- proteasome (prosome, macropain) 26S subunit, ATPase 2
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