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PSMA1 Products

(Proteasome Subunit alpha Type 1 (PSMA1))
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009].

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Featured PSMA1 Categories

PSMA1 Antibodies

High quality antibodies with extensive validation data.

PSMA1 ELISA Kits

Reliable ELISA kits for a wide range of species.

PSMA1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PSMA1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, RNAi
Validations
  • (1)
  • (5)
Cat. No. ABIN562469
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF, IP
Validations
  • (5)
Cat. No. ABIN7164944
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN3016184
Quantity 100 μL
Datasheet Datasheet

Recommended PSMA1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958894
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4884280
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385261
Quantity 96 tests
Datasheet Datasheet

Recommended PSMA1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124639
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316548
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2131373
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PSMA1 products

Liu, Tsai, Morleo, Oh, Leitch, Massa, Lee, Parker, Finley, Zaghloul, Franco, Katsanis: "Ciliopathy proteins regulate paracrine signaling by modulating proteasomal degradation of mediators." in: The Journal of clinical investigation, Vol. 124, Issue 5, pp. 2059-70, (2014) (PubMed).

Cron, Zhu, Kushwaha, Hsieh, Merzon, Rameseder, Chen, DAndrea, Kozono: "Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer." in: PLoS ONE, Vol. 8, Issue 9, pp. e73710, (2013) (PubMed).

Ma, Geng, Xu, Wu, He, Shu, Huang, Du, Li: "The role of translationally controlled tumor protein in tumor growth and metastasis of colon adenocarcinoma cells." in: Journal of proteome research, Vol. 9, Issue 1, pp. 40-9, (2010) (PubMed).

Laporte, Salin, Daignan-Fornier, Sagot: "Reversible cytoplasmic localization of the proteasome in quiescent yeast cells." in: The Journal of cell biology, Vol. 181, Issue 5, pp. 737-45, (2008) (PubMed).

Vishnyakova, Kurlander, Bocharov, Baranova, Chen, Abu-Asab, Tsokos, Malide, Basso, Remaley, Csako, Eggerman, Patterson: "CLA-1 and its splicing variant CLA-2 mediate bacterial adhesion and cytosolic bacterial invasion in mammalian cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 45, pp. 16888-93, (2006) (PubMed).

Funakoshi, Sasaki, Nishimoto, Kobayashi: "Budding yeast Dsk2p is a polyubiquitin-binding protein that can interact with the proteasome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 2, pp. 745-50, (2002) (PubMed).

Lelouard, Gatti, Cappello, Gresser, Camosseto, Pierre: "Transient aggregation of ubiquitinated proteins during dendritic cell maturation." in: Nature, Vol. 417, Issue 6885, pp. 177-82, (2002) (PubMed).

Xie, Varshavsky: "UFD4 lacking the proteasome-binding region catalyses ubiquitination but is impaired in proteolysis." in: Nature cell biology, Vol. 4, Issue 12, pp. 1003-7, (2002) (PubMed).

Voges, Zwickl, Baumeister: "The 26S proteasome: a molecular machine designed for controlled proteolysis." in: Annual review of biochemistry, Vol. 68, pp. 1015-68, (2000) (PubMed).

Kopp, Hendil, Dahlmann, Kristensen, Sobek, Uerkvitz: "Subunit arrangement in the human 20S proteasome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 7, pp. 2939-44, (1997) (PubMed).

Synonyms and alternative names related to PSMA1

proteasome subunit alpha 1 (PSMA1), proteasome subunit alpha 1 (psma1), proteasome subunit alpha type 1 (CNB05540), 20S proteasome subunit C2 (psmA1), proteasome (prosome, macropain) subunit, alpha type 1 (Psma1), proteasome subunit alpha 1 (Psma1), proteasome subunit alpha 1 L homeolog (psma1.L), Proteasome alpha6 subunit (Prosalpha6), 143314_at, Alpha-6, alpha-type, alpha6, alpha_dm, anon-SAGE:Wang-116, C2, CC2, CG4904, DDBDRAFT_0204226, DDBDRAFT_0214956, DDB_0204226, DDB_0214956, Dmel\CG4904, HC2, NU, Pros-30, PROS-35, Pros-35, PROS-Dm35, Pros-Dm35, pros30, PROS30, pros 35, pros35, Prosalpha6, PSMA1, zgc:92726

Protein level used designations for PSMA1

  • proteasome (prosome, macropain) subunit, alpha type, 1
  • proteasome subunit alpha type-1
  • proteasome subunit alpha type 1
  • 20S proteasome subunit alpha-1
  • 20S proteasome subunit C2
  • macropain subunit C2
  • multicatalytic endopeptidase complex subunit C2
  • proteasome component C2
  • proteasome nu chain
  • proteasome alpha 1 subunit
  • 30 kDa prosomal protein
  • PROS-30
  • macropain subunit nu
  • proteasome subunit nu
  • proteasome subunit, alpha-type, 1
  • protein P30-33K
  • proteasome subunit alpha type
  • 20s proteasome
  • CG4904-PA
  • Pros35-PA
  • alpha6
  • anon-SAGE:Wang-116
  • proteasome 35
  • proteasome 35 kD subunit
  • proteasome 35-kDa subunit
  • proteasome 35kD subunit
  • proteasome 35kDa subunit
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