KIT Ligand Protein (KITLG)
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- Target See all KIT Ligand (KITLG) Proteins
- KIT Ligand (KITLG)
- Biological Activity
- Active
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Origin
- Human
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Source
- Yeast (Pichia pastoris)
- Sequence
- MEGICRNRVT NNVKDVTKLV ANLPKDYMIT LKYVPGMDVL PSHCWISEMV VQLSDSLTDL LDKFSNISEG LSNYSIIDKL VNIVDDLVEC VKENSSKDLK KSFKSPEPRL FTPEEFFRIF NRSIDAFKDF VVASETSDCV VSSTLSPEKD SRVSVTKPFM LPPVanalys is The sequence of the first five N-terminal amino acids has been found to be Met-Glu-Gly-Ile-Cys
- Characteristics
- The ED50, as determined by the dose-dependant stimulation of human TF-1 cells, is < 2 ng/ml, corresponding to a specific activity of 5×105 IU/mg.
- Purity
- > 95 % by SDS-PAGE
- Endotoxin Level
- level is less than 0.1 ng per myg (1 EU/myg) of human SC
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Storage
- -20 °C
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- Target
- KIT Ligand (KITLG)
- Alternative Name
- Stem Cell Factor (SCF) (KITLG Products)
- Synonyms
- Xkl-1 Protein, Xsl Protein, Xsl-1 Protein, Xsl-2 Protein, steel Protein, KITLG Protein, SCF Protein, kitl Protein, kl-1 Protein, mgf Protein, scf Protein, FPH2 Protein, KL-1 Protein, Kitl Protein, MGF Protein, SF Protein, SHEP7 Protein, Clo Protein, Con Protein, Gb Protein, Kitlg Protein, Mgf Protein, SLF Protein, Sl Protein, blz Protein, contrasted Protein, 710-712 Protein, CSF Protein, KITL Protein, KIT ligand L homeolog Protein, KIT ligand Protein, kit ligand Protein, kitlg.L Protein, KITLG Protein, kitlg Protein, Kitl Protein, Kitlg Protein
- Background
- SCF is a hematopoietic growth factor that exerts its activity during the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors.SCF, P. Pichia Derived, human, is a single, glycosylated polypeptide chain containing 165 amino acids and having a molecular mass of ~20 KDa. Synonym: Stem Cell Factor (SCF), human 7. Formulation: Lyophilized from 10 mM Acetic acid.
- Molecular Weight
- ~20 KDa
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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