SDF1 beta Protein

Catalog No. ABIN988233

Product Details

Target: SDF1 beta (SDF1b) (Stromal Cell Derived Factor 1 beta (SDF1b))

Biological Activity: Active

Origin: Rat

Source: Escherichia coli (E. coli)

Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL K

Characteristics: Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human peripheral blood monocytes is less than 200 ng/ml, corresponding to a specific activity of >, 5.0 × 103 IU/mg.

Purity: > 97 % by SDS-PAGE and HPLC analyses.

Endotoxin Level: Level Less than 1EU/µg of rRtSDF-1beta/CXCL12 as determined by LAL method

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

Storage: 4 °C

Target Details

Target: SDF1 beta (SDF1b) (Stromal Cell Derived Factor 1 beta (SDF1b))

Alternative Name: SDF-1 beta/cxcl12 (SDF1b Products)

Synonyms: Pbsf Protein, Scyb12 Protein, Sdf1 Protein, Tlsf Protein, Tpar1 Protein, sdf1a Protein, SDF-1 Protein, chemokine (C-X-C motif) ligand 12 Protein, C-X-C motif chemokine ligand 12 Protein, Cxcl12 Protein, cxcl12 Protein, CXCL12 Protein

Background: SDF-1ª and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor. SDF-1ª and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor. Synonym: SDF-1beta/CXCL12, Rat. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.

Molecular Weight: 7.9 kDa, a single non-glycosylated polypeptide chain containing 72 amino acids.