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PTH Protein (AA 1-34)

PTH Origin: Human Host: Escherichia coli (E. coli) > 97 % by SDS-PAGE and HPLC analyses. Active
Catalog No. ABIN988194
  • Target See all PTH Proteins
    PTH (Parathyroid Hormone (PTH))
    Biological Activity
    Active
    Protein Characteristics
    AA 1-34
    Origin
    • 17
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 20
    • 8
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    SVSEIQLMHN LGKHLNSMER VEWLRKKLQD VHN
    Characteristics
    Fully biologically active when compared to standard. The specific activity is determined by UMR106 cell/cAMP method, corresponding to a specific activity of >, 1.0 × 104 IU/mg.
    Purity
    > 97 % by SDS-PAGE and HPLC analyses.
    Endotoxin Level
    Level Less than 1EU/µg of rHuPTH1-34 as determined by LAL method
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    Discover our top product PTH Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
    Storage
    4 °C
  • Target
    PTH (Parathyroid Hormone (PTH))
    Alternative Name
    Parathyroid Hormone( PTH) (PTH Products)
    Synonyms
    PTH1 Protein, Pthp Protein, PTH-(1-84) Protein, Pth1 Protein, Pthr1 Protein, PTH Protein, parathyroid hormone Protein, parathyroid hormone S homeolog Protein, PTH Protein, Pth Protein, pth.S Protein
    Target Type
    Hormone
    Background
    Polypeptide hormones secreted by the parathyroid glands, which promote release of calcium from bone to extracellular fluid by activating osteoblasts and inhibiting osteoclasts, indirectly promote increased intestinal absorption of calcium, and promote renal tubular reabsorption of calcium and increased renal excretion of phosphates. It is a major regulator of bone metabolism. Secretion of parathyroid hormone increases when the level of calcium in the extracellular fluid is low. Its action is opposed by calcitonin. Synonym: Parathyroid Hormone 1-34 ( PTH 1-34 ), Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.0, containing 4% mannitol.
    Molecular Weight
    4117.8 Da, a single non-glycosylated polypeptide chain containing 34 amino acids.
    Pathways
    cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
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