CCL22 Protein

Catalog No. ABIN988140

Product Details

Target: CCL22 (Chemokine (C-C Motif) Ligand 22 (CCL22))

Biological Activity: Active

Origin: Mouse

Source: Escherichia coli (E. coli)

Sequence: GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITVKNRD ICADPRQVWV KKLLHKL

Characteristics: Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human activated lymphocytes is less than 100 ng/ml, corresponding to a specific activity of >, 1.0 × 104 IU/mg.

Purity: > 97 % by SDS-PAGE and HPLC analyses.

Endotoxin Level: Level Less than 1EU/µg of rMuMDC/CCL22 as determined by LAL method

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

Storage: 4 °C

Target Details

Target: CCL22 (Chemokine (C-C Motif) Ligand 22 (CCL22))

Alternative Name: MDC/CCL22 (CCL22 Products)

Synonyms: ABCD-1 Protein, DC/B-CK Protein, MDC Protein, SCYA22 Protein, STCP-1 Protein, DCBCK Protein, Scya22 Protein, Mdc Protein, CCL22 Protein, C-C motif chemokine ligand 22 Protein, chemokine (C-C motif) ligand 22 Protein, CCL22 Protein, Ccl22 Protein

Background: MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. Synonym: MDC/CCL22, Mouse. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl.

Molecular Weight: 7.8 kDa, a single, non-glycosylated polypeptide chain containing 68 amino acids.