CCL13 Protein
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- Target See all CCL13 Proteins
- CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLK
- Characteristics
- Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is less than 100 ng/ml, corresponding to a specific activity of >, 1.0 × 104 IU/mg.
- Purity
- > 96 % by SDS-PAGE and HPLC analyses.
- Endotoxin Level
- Level Less than 1EU/µg of rHuMCP-4/CCL13 as determined by LAL method
- Top Product
- Discover our top product CCL13 Protein
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Chemokine (C-C Motif) Ligand 13 (CCL13) (Active) protein
CCL13 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Chemokine (C-C Motif) Ligand 13 (CCL13) (AA 24-98) protein (His tag)CCL13 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 13 (CCL13) (AA 1-98) protein (GST tag)CCL13 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 13 (CCL13) (AA 17-98) protein (His tag)CCL13 Origin: Human Host: Yeast (Pichia pastoris) Recombinant > 95 % WB, SDS, ELISA, IP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
- Storage
- 4 °C
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- Target
- CCL13 (Chemokine (C-C Motif) Ligand 13 (CCL13))
- Alternative Name
- MCP-4/CCL13 (CCL13 Products)
- Synonyms
- CKb10 Protein, MCP-4 Protein, NCC-1 Protein, NCC1 Protein, SCYA13 Protein, SCYL1 Protein, C-C motif chemokine ligand 13 Protein, chemokine (C-C motif) ligand 13 Protein, CCL13 Protein
- Background
- CCL13 is a chemoattractant for monocytes and eosinophils, and activates basophils. In addition, it has been reported to be chemotactic for CD4+ and CD8+ T cells, with an activity almost equivalent to that of MCP-3. The bioactivities of CCL13 is most likely mediated by the CC chemokine receptors CCR-2 and CCR-3, both of which have been shown to bind CCL13. Synonym: MCP-4/CCL13, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 130mM NaCl.
- Molecular Weight
- 8.6 kDa, a single non-glycosylated polypeptide chain containing 75 amino acids.
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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