CCL21 Protein
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- Target See all CCL21 Proteins
- CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCR KTERSQTPKG
- Characteristics
- Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human peripheral blood T-lymphocytes is less than 600 ng/ml, corresponding to a specific activity of >, 1.7 × 103 IU/mg.
- Purity
- > 97 % by SDS-PAGE and HPLC analyses.
- Endotoxin Level
- Level Less than 1EU/µg of rHuExodus/CCL21 as determined by LAL method
- Top Product
- Discover our top product CCL21 Protein
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Chemokine (C-C Motif) Ligand 21 (CCL21) (Active) protein
CCL21 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Chemokine (C-C Motif) Ligand 21 (CCL21) (AA 24-133) protein (His tag)CCL21 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 21 (CCL21) (AA 1-134) protein (GST tag)CCL21 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
- Storage
- 4 °C
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- Target
- CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))
- Alternative Name
- Exodus-2/CCL21 (CCL21 Products)
- Synonyms
- 6Ckine Protein, CKb9 Protein, ECL Protein, SCYA21 Protein, SLC Protein, TCA4 Protein, ccl21 Protein, Ccl21b Protein, C-C motif chemokine ligand 21 Protein, C-C motif chemokine 21 Protein, CCL21 Protein, ccl21 Protein, Ccl21 Protein
- Background
- Exodus-2/CCL21 is a novel CC chemokine discovered independently by three groups from the EST database, and shows 21-33% identity to other CC chemokines. Exodus-2 contains the four conserved cysteines characteristic of beta chemokines plus two additional cysteines in its unusually long carboxylterminal domain. It is expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Synonym: Exodus-2/CCL21, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4,150mM NaCl.
- Molecular Weight
- 12.2 kDa, a single, non-glycosylated polypeptide chain containing 111 amino acids.
- Pathways
- Regulation of Actin Filament Polymerization
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