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WISP1 Protein

WISP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Catalog No. ABIN935909
  • Target See all WISP1 Proteins
    WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 5
    • 4
    • 1
    Human
    Source
    • 5
    • 3
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    TALSPAPTTM DFTPAPLEDT SSRPQFCKWP CECPPSPPRC PLGVSLITDG CECCKMCAQQ LGDNCTEAAI CDPHRGLYCD YSGDRPRYAI GVCAQVVGVG CVLDGVRYNN GQSFQPNCKY NCTCIDGAVG CTPLCLRVRP PRLWCPHPRR VSIPGHCCEQ WVCEDDAKRP RKTAPRDTGA FDAVGEVEAW HRNCIAYTSP WSPCSTSCGL GVSTRISNVN AQCWPEQESR LCNLRPCDVD IHTLIKAGKK CLAVYQPEAS MNFTLAGCIS TRSYQPKYCG VCMDNRCCIP YKSKTIDVSF QCPDGLGFSR QVLWINACFC NLSCRNPNDI FADLESYPDF SEIAN
    Characteristics
    Purified recombinant Human WISP1 protein
    Expression System: E.coli
    Bioactivity: The ED50 was determined by the dose-dependant proliferation of the MCF-7 cell line. The expected ED50 for this effect is 1.0-3.0 µg/mL.
    Purity
    > 98 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
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    Discover our top product WISP1 Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL (this product is slow to dissolve)
    Buffer
    Lyophilized from 10 mM CH3COOH.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))
    Alternative Name
    WISP1 (WISP1 Products)
    Background
    WISP-1 is a member of the CCN family of secreted cysteine rich regulatory proteins. It is expressed in the heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. WISP-1 is a beta catenin regulated protein that can contribute to tumorigenesis and has also been shown to play a role in bone development and fracture repair. Human WISP-1 is a 38.1 kDa protein containing 346 amino acid residues. It is composed of four distinct structural domains (modules), the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the thrombospondin type-1 repeat (TSP type-1) domain, and a C-terminal cystine knot-like (CTCK) domain.
    Alternative Names: WNT-1 inducible signaling pathway protein-1 protein, CCN4 protein, WISP-1 protein, WISP-1, WISP1, WISP 1 protein, Wnt-1-induced secreted protein protein, WISP-1 protein, WISP 1
    Pathways
    WNT Signaling, Growth Factor Binding
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