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TWSG1 Protein

TWSG1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Catalog No. ABIN935873
  • Target See all TWSG1 Proteins
    TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 5
    • 2
    • 2
    • 1
    • 1
    Human
    Source
    • 5
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    MCNKALCASD VSKCLIQELC QCRPGEGNCS CCKECMLCLG ALWDECCDCV GMCNPRNYSD TPPTSKSTVE ELHEPIPSLF RALTEGDTQL NWNIVSFPVA EELSHHENLV SFLETVNQPH HQNVSVPSNN VHAPYSSDKE HMCTVVYFDD CMSIHQCKIS CESMGASKYR WFHNACCECI GPECIDYGSK TVKCMNCMF
    Characteristics
    Purified recombinant Human TSG protein
    Expression System: E.coli
    Bioactivity: Determined by its ability to neutralize BMP-6 induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is
    Purity
    > 98 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
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  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))
    Alternative Name
    TSG (TWSG1 Products)
    Synonyms
    TWSG1 Protein, TSG Protein, DKFZp469J051 Protein, 1810013J15Rik Protein, 9030422N06Rik Protein, AW552143 Protein, D17Ertd403e Protein, Tsg Protein, Twg Protein, fi23f01 Protein, tsg Protein, tsga Protein, twsg1 Protein, wu:fi23f01 Protein, twsg Protein, tsg1 Protein, tsgb Protein, ztsg1 Protein, twisted gastrulation BMP signaling modulator 1 Protein, twisted gastrulation homolog 1 (Drosophila) Protein, twisted gastrulation BMP signaling modulator 1a Protein, twisted gastrulation BMP signaling modulator 1 S homeolog Protein, twisted gastrulation BMP signaling modulator 1 L homeolog Protein, twisted gastrulation BMP signaling modulator 1b Protein, TWSG1 Protein, Twsg1 Protein, twsg1a Protein, twsg1.S Protein, twsg1.L Protein, twsg1b Protein
    Background
    Twisted Gastrulation Protein (TSG) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins, and can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex.
    Alternative Names: Twisted Gastrulation Protein protein
    Molecular Weight
    22.2 kDa
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