Relaxin 3 Protein (RLN3)

Catalog No. ABIN935768

Product Details

Target: Relaxin 3 (RLN3)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Sequence: RAAPYGVRL CGREFIRAVI FTCGGSRW

Characteristics: Purified recombinant Human Relaxin 3 protein
Expression System: E.coli

Purity: > 98 % pure

Endotoxin Level: < 0.1 ng per µg (1 EU/µg).

Application Details

Application Notes: Each Investigator should determine their own optimal working dilution for specific applications.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Supplied as a lyophilized powder.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Target Details

Target: Relaxin 3 (RLN3)

Alternative Name: Relaxin 3 (RLN3 Products)

Background: Relaxin-3 (H3 relaxin, Insulin-like peptide-7, INSL7) is a secreted protein structurally related to insulin, which is expressed primarily in the brain and central nervous system. Relaxin-3 has been identified as the ligand for the GPCR135 receptor, previously known as "somatostatin-like" or "angiotensin-like" peptide receptor, and also binds specifically to the LGR7 receptor, previously identified as an "orphan" G protein coupled receptor. Signaling by Relaxin-3 through its target receptors is, most likely, part of a CNS processing system, activated in response to signaling by neuropeptides and other factors. Intracerebroventricular injections of Relaxin-3 have been shown to cause a significant increase of food intake and body weight in Wistar rats.
Alternative Names: Relaxin-3 protein, Relaxin-3 protein, INSL7 protein, Relaxin-3, H3 relaxin protein, Insulin-like peptide-7 protein, Relaxin 3, Relaxin 3 protein, Relaxin 3

Molecular Weight: 5.5 kDa

Pathways: Hormone Activity, cAMP Metabolic Process