Relaxin 3 Protein (RLN3)
RLN3
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 98 % pure
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- Target See all Relaxin 3 (RLN3) Proteins
- Relaxin 3 (RLN3)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- RAAPYGVRL CGREFIRAVI FTCGGSRW
- Characteristics
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Purified recombinant Human Relaxin 3 protein
Expression System: E.coli - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- Relaxin 3 (RLN3)
- Alternative Name
- Relaxin 3 (RLN3 Products)
- Synonyms
- RFLB Protein, RLX3 Protein, RFLC2 Protein, rln3 Protein, rlx 3a Protein, rlx3a Protein, rxn3 Protein, RFLCI Protein, insl7 Protein, zins4 Protein, H3 Protein, RXN3 Protein, ZINS4 Protein, M3 Protein, Insl7 Protein, Relaxin-3 Protein, relaxin 3 Protein, relaxin 3a Protein, RLN3 Protein, rln3a Protein, rln3 Protein, Rln3 Protein
- Background
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Relaxin-3 (H3 relaxin, Insulin-like peptide-7, INSL7) is a secreted protein structurally related to insulin, which is expressed primarily in the brain and central nervous system. Relaxin-3 has been identified as the ligand for the GPCR135 receptor, previously known as "somatostatin-like" or "angiotensin-like" peptide receptor, and also binds specifically to the LGR7 receptor, previously identified as an "orphan" G protein coupled receptor. Signaling by Relaxin-3 through its target receptors is, most likely, part of a CNS processing system, activated in response to signaling by neuropeptides and other factors. Intracerebroventricular injections of Relaxin-3 have been shown to cause a significant increase of food intake and body weight in Wistar rats.
Alternative Names: Relaxin-3 protein, Relaxin-3 protein, INSL7 protein, Relaxin-3, H3 relaxin protein, Insulin-like peptide-7 protein, Relaxin 3, Relaxin 3 protein, Relaxin 3 - Molecular Weight
- 5.5 kDa
- Pathways
- Hormone Activity, cAMP Metabolic Process
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