Cardiotrophin 2 Protein (CTF2)
CTF2
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 98 % pure
Active
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- Target See all Cardiotrophin 2 (CTF2) Proteins
- Cardiotrophin 2 (CTF2)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Sequence
- MAPISPSEPI GQAYSLALYM QKNTSALLQT YLQHQGSPFS DPGFSAPELQ LSTLPSAAVS FKTWHAMEDA ERLSRAQGAF LALTQHLQLV GDDQSYLNPG SPILLAQLGA ARLRAQGLLG NMAAIMTALG LPIPPEEDTL GFVPFGASAF ERKCRGYIVT REYGHWTDRA VRDLALLKAK YSA
- Characteristics
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Purified recombinant Mouse Neuropoietin protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is 0.5-0.8 µg/mL. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- Cardiotrophin 2 (CTF2)
- Alternative Name
- Neuropoietin (CTF2 Products)
- Synonyms
- Gm494 Protein, NP Protein, Ctf2p Protein, cardiotrophin 2 Protein, cardiotrophin-like cytokine factor 1 Protein, Ctf2 Protein, CLCF1 Protein
- Background
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Neuropoietin is a newly identified member of the IL6 cytokine family. Members of this family, including IL6, IL11, oncostatin M, leukemia inhibitory factor (LIF), cardiotrophin-1 (CT-1), cardiotrophin-like cytokine, and CNTF, display a four-helix bundle structure, and signal through gp130-containing receptor complexes. Neuropoietin, which is predominantly expressed in neuroepithelia during embryonic life, acts through a receptor complex comprising CNTF receptor-a component, gp 130, and LIF receptor. Like CNTF, it promotes the survival of embryonic motor neurons and could increase the proliferation of neural precursor cells in the presence of EGF and FGF2.
Alternative Names: NPO protein, NP protein - Molecular Weight
- 19.8 kDa
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