NPX1 Protein
NPX1
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 98 % pure
Active
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- Target See all NPX1 Proteins
- NPX1 (Neuronal Pentraxin 1 (NPX1))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- ACYCRIPACI AGERRYGYCI YQGRLWAFCC
- Characteristics
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Purified recombinant Human NP1 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract immature dendritic cells using a concentration of 1.0-10.0 ng/mL. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product NPX1 Protein
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Neuronal Pentraxin 1 (NPX1) (AA 141-240) protein (GST tag)
NPX1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Neuronal Pentraxin 1 (NPX1) protein (Myc-DYKDDDDK Tag)NPX1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- NPX1 (Neuronal Pentraxin 1 (NPX1))
- Alternative Name
- NP1 (NPX1 Products)
- Synonyms
- NP1 Protein, D11Bwg1004e Protein, Np1 Protein, np1 Protein, nptx1 Protein, neuronal pentraxin 1 Protein, neuronal pentraxin 1 L homeolog Protein, Nptx1 Protein, NPTX1 Protein, nptx1 Protein, nptx1.L Protein
- Background
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Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins which include NP-1, NP-2 and NP-3, are distinguished from the beta-defensins by the pairing of their three disulfide bonds. In addition to antimicrobial activity, NP-1 exhibits chemotactic activity on dendritic cells. NP-1 is expressed as the C-terminal portion of an inactive precursor protein, which also contains a 19 amino acid N-terminal signal sequence and a 45 amino acid polypeptide. NP-1 contains a six-cysteine motif that forms three intra-molecular disulfide bonds.
Alternative Names: NP 1 protein, NP 1, Cryptdin protein, alpha Defensin-1 protein, Neutrophil Peptide-1 protein, HNP-1 protein, NP1, NP-1, NP-1 protein, NP-1 protein - Molecular Weight
- 3.4 kDa
- Pathways
- Carbohydrate Homeostasis, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, SARS-CoV-2 Protein Interactome
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