GZMB Protein
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- Target See all GZMB Proteins
- GZMB (Granzyme B (GZMB))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Baculovirus
- Sequence
- IIGGHEVKPH SRPYMALLSI KDQQPEAICG GFLIREDFVL TAAHCEGSII NVTLGAHNIK EQEKTQQVIP MVKCIPHPDY NPKTFSNDIM LLKLKSKAKR TRAVRPLNLP RRNVNVKPGD VCYVAGWGRM APMGKYSNTL QEVELTVQKD RECESYFKNR YNKTNQICAG DPKTKRASFR GDSGGPLVCK KVAAGIVSYG YKDGSPPRAF TKVSSFLSWI KKTMKSS
- Characteristics
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Purified recombinant Mouse Granzyme B protein
Expression System: Baculovirus
Bioactivity: Determined by its ability to cleave a synthetic chromogentic Granzyme B substrate. The expected specific activity , when using the Ac-IEPD-pNA substrate at 250C, is greater than 750 nM/min per µg of enzyme. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product GZMB Protein
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Granzyme B (GZMB) (AA 148-247) protein (GST tag)
GZMB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) (AA 21-247) protein (GST tag)GZMB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) (AA 1-247) protein (GST tag)GZMB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) protein (His tag)GZMB Origin: Mouse Host: Human Cells Recombinant > 85 % as determined by SDS-PAGE
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
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- Target
- GZMB (Granzyme B (GZMB))
- Alternative Name
- Granzyme B (GZMB Products)
- Synonyms
- CCPI Protein, CGL-1 Protein, CGL1 Protein, CSP-B Protein, CSPB Protein, CTLA1 Protein, CTSGL1 Protein, HLP Protein, SECT Protein, granzyme B Protein, GZMB Protein
- Background
- Granzyme B is a cysteine protease found in the cytoplasmic granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme B is required for the induction of target cell lysis, which occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms. Proteolytic cleavage of substrates by Granzyme B takes place primarily after aspartic acid residues. Recombinant Mouse.
- Molecular Weight
- 28.9 kDa
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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