GDF11 Protein
GDF11
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 98 % pure
Active
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- Target See all GDF11 Proteins
- GDF11 (Growth Differentiation Factor 11 (GDF11))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- NLGLDCDEHS SESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGQCEYM FMQKYPHTHL VQQANPRGSA GPCCTPTKMS PINMLYFNDK QQIIYGKIPG MVVDRCGCS
- Characteristics
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Purified recombinant Human GDF11 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The expected ED50 for this effect is 0.08-0.10 µg/mL. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product GDF11 Protein
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Growth Differentiation Factor 11 (GDF11) (AA 310-407) protein (GST tag)
GDF11 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Keep pH below 5.0.
- Buffer
- Supplied lyophilized with no additives.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
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- Target
- GDF11 (Growth Differentiation Factor 11 (GDF11))
- Alternative Name
- GDF11 (GDF11 Products)
- Synonyms
- BMP-11 Protein, BMP11 Protein, Bmp11 Protein, GDF11 Protein, growth differentiation factor 11 Protein, GDF11 Protein, Gdf11 Protein, gdf11 Protein
- Background
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GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth. GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase. Similarities between myostatin and GDF-11, which are 90 % identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same.
Alternative Names: BMP-11 protein, GDF 11 protein, GDF-11 protein, GDF-11 protein, GDF-11, Growth/Differentiation Factor-11 protein, GDF11, GDF 11 - Molecular Weight
- 25 kDa
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