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FGF23 Protein

FGF23 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % pure
Catalog No. ABIN935370
  • Target See all FGF23 Proteins
    FGF23 (Fibroblast Growth Factor 23 (FGF23))
    Protein Type
    Recombinant
    Origin
    • 15
    • 4
    • 3
    • 1
    Human
    Source
    • 13
    • 5
    • 2
    • 1
    Escherichia coli (E. coli)
    Sequence
    MYPNASPLLG SSWGGLIHLY TATARNSYHL QIHKNGHVDG APHQTIYSAL MIRSEDAGFV VITGVMSRRY LCMDFRGNIF GSHYFDPENC RFQHQTLENG YDVYHSPQYH FLVSLGRAKR AFLPGMNPPP YSQFLSRRNE IPLIHFNTPI PRRHTRSAED DSERDPLNVL KPRARMTPAP ASCSQELPSA EDNSPMASDP LGVVRGGRVN THAGGTGPEG CRPFAKFI
    Characteristics
    Purified recombinant Human FGF23 protein
    Expression System: E.coli
    Purity
    > 95 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product FGF23 Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Supplied as a lyophilized powder.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    RT/-20 °C
  • Target
    FGF23 (Fibroblast Growth Factor 23 (FGF23))
    Alternative Name
    FGF23 (FGF23 Products)
    Synonyms
    FGF23 Protein, ADHR Protein, FGFN Protein, HPDR2 Protein, HYPF Protein, PHPTC Protein, fibroblast growth factor 23 Protein, fgf23 Protein, FGF23 Protein, Fgf23 Protein
    Background
    The FGF family plays a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF23, FGF21 and FGF19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1.
    Alternative Names: FGF-23 protein, FGF-23, FGF23, FGF 23, Fibroblast Growth Factor-23 protein, FGF 23 protein, FGF-23 protein
    Molecular Weight
    22.5 kDa
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
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