DLL1 Protein
-
- Target See all DLL1 Proteins
- DLL1 (delta-Like 1 (DLL1))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Human
-
Source
- HEK-293T Cells
- Sequence
- SGVFELKLQE FVNKKGLLGN RNCCRGGAGP PPCACRTFFR VCLKHYQASV SPEPPCTYGS AVTPVLGVDS FSLPDGGGAD SAFSNPIRFP FGFTWPGTFS LIIEALHTDS PDDLATENPE RLISRLATQR HLTVGEEWSQ DLHSSGRTDL KYSYRFVCDE HYYGEGCSVF CRPRDDAFGH FTCGERGEKV CNPGWKGPYC TEPICLPGCD EQHGFCDKPG ECKCRVGWQG RYCDECIRYP GCLHGTCQQP WQCNCQEGWG GLFCNQDLNY CTHHKPCKNG ATCTNTGQGS YTCSCRPGYT GATCELGIDE CDPSPCKNGG SCTDLENSYS CTCPPGFYGK ICELSAMTCA DGPCFNGGRC SDSPDGGYSC RCPVGYSGFN CEKKIDYCSS SPCSNGAKCV DLGDAYLCRC QAGFSGRHCD DNVDDCASSP CANGGTCRDG VNDFSCTCPP GYTGRNCSAP VSRCEHAPCH NGATCHERGH RYVCECARGY GGPNCQFLLP ELPPGPAVVD LTEKLEGQGG PF
- Characteristics
-
Purified recombinant Human sDLL1 protein
Expression System: 293 cells
Bioactivity: Determined by the dose dependent growth suppression of the human acute mon °Cytic leukemia cell line, THP-1. sDLL-1 inhibits the proliferation in THP-1 cells using a concentration of 3.0-5.0 µg/mL. - Purity
- > 95 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product DLL1 Protein
-
delta-Like 1 (DLL1) (AA 18-540) protein (His tag)
DLL1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
delta-Like 1 (DLL1) protein (Fc Tag)DLL1 Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
delta-Like 1 (DLL1) (AA 18-109) protein (GST tag)DLL1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
delta-Like 1 (DLL1) (Active) protein (His tag)DLL1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
delta-Like 1 (DLL1) (AA 1-545), (Extracellular Domain) (Active) protein (Fc Tag)DLL1 Origin: Human Host: CHO Cells Recombinant >90 % (SDS-PAGE) SDS Active
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- Lyophilized from PBS, pH 7.5,.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
-
- Target
- DLL1 (delta-Like 1 (DLL1))
- Alternative Name
- sDLL1 (DLL1 Products)
- Synonyms
- X-delta-1 Protein, XDelta1 Protein, Xdelta-1 Protein, delta Protein, delta-1 Protein, delta1 Protein, x-delta Protein, DELTA1 Protein, DL1 Protein, Delta Protein, DLK Protein, DLK-1 Protein, Delta1 Protein, FA1 Protein, PREF1 Protein, Pref-1 Protein, ZOG Protein, pG2 Protein, DLL1 Protein, AW742678 Protein, DlkI Protein, Ly107 Protein, Peg9 Protein, SCP1 Protein, pref-1 Protein, delta-like 1 Protein, delta like canonical Notch ligand 1 Protein, delta like non-canonical Notch ligand 1 Protein, delta-like 1 L homeolog Protein, delta-like 1 (Drosophila) Protein, delta-like 1 homolog (Drosophila) Protein, dll1 Protein, DLL1 Protein, DLK1 Protein, Dll1 Protein, dll1.L Protein, Dlk1 Protein
- Background
-
Human sDLL-1 comprises the extracellular signaling domain of DLL1, a member of a structurally-related family of single-pass type I trans-membrane proteins that serve as ligands for Notch receptors. It is expressed in the heart and pancreas, and to a lesser extent in various other tissues. DLL-1 functions to specifically activate the Notch-1 and Notch-2 receptors.
Alternative Names: sDLL-1 protein, Delta-like protein 1 protein, Delta-1 protein, sDLL1, sDLL 1 protein, sDLL 1, sDLL-1 protein, sDLL-1 - Molecular Weight
- 57-60 kDa
- Pathways
- Notch Signaling, Stem Cell Maintenance
-
