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DLL1 Protein

DLL1 Origin: Human Host: HEK-293T Cells Recombinant > 95 % pure Active
Catalog No. ABIN935315
  • Target See all DLL1 Proteins
    DLL1 (delta-Like 1 (DLL1))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 11
    • 2
    • 2
    Human
    Source
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293T Cells
    Sequence
    SGVFELKLQE FVNKKGLLGN RNCCRGGAGP PPCACRTFFR VCLKHYQASV SPEPPCTYGS AVTPVLGVDS FSLPDGGGAD SAFSNPIRFP FGFTWPGTFS LIIEALHTDS PDDLATENPE RLISRLATQR HLTVGEEWSQ DLHSSGRTDL KYSYRFVCDE HYYGEGCSVF CRPRDDAFGH FTCGERGEKV CNPGWKGPYC TEPICLPGCD EQHGFCDKPG ECKCRVGWQG RYCDECIRYP GCLHGTCQQP WQCNCQEGWG GLFCNQDLNY CTHHKPCKNG ATCTNTGQGS YTCSCRPGYT GATCELGIDE CDPSPCKNGG SCTDLENSYS CTCPPGFYGK ICELSAMTCA DGPCFNGGRC SDSPDGGYSC RCPVGYSGFN CEKKIDYCSS SPCSNGAKCV DLGDAYLCRC QAGFSGRHCD DNVDDCASSP CANGGTCRDG VNDFSCTCPP GYTGRNCSAP VSRCEHAPCH NGATCHERGH RYVCECARGY GGPNCQFLLP ELPPGPAVVD LTEKLEGQGG PF
    Characteristics
    Purified recombinant Human sDLL1 protein
    Expression System: 293 cells
    Bioactivity: Determined by the dose dependent growth suppression of the human acute mon °Cytic leukemia cell line, THP-1. sDLL-1 inhibits the proliferation in THP-1 cells using a concentration of 3.0-5.0 µg/mL.
    Purity
    > 95 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
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  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from PBS, pH 7.5,.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    RT/-20 °C
  • Target
    DLL1 (delta-Like 1 (DLL1))
    Alternative Name
    sDLL1 (DLL1 Products)
    Synonyms
    X-delta-1 Protein, XDelta1 Protein, Xdelta-1 Protein, delta Protein, delta-1 Protein, delta1 Protein, x-delta Protein, DELTA1 Protein, DL1 Protein, Delta Protein, DLK Protein, DLK-1 Protein, Delta1 Protein, FA1 Protein, PREF1 Protein, Pref-1 Protein, ZOG Protein, pG2 Protein, DLL1 Protein, AW742678 Protein, DlkI Protein, Ly107 Protein, Peg9 Protein, SCP1 Protein, pref-1 Protein, delta-like 1 Protein, delta like canonical Notch ligand 1 Protein, delta like non-canonical Notch ligand 1 Protein, delta-like 1 L homeolog Protein, delta-like 1 (Drosophila) Protein, delta-like 1 homolog (Drosophila) Protein, dll1 Protein, DLL1 Protein, DLK1 Protein, Dll1 Protein, dll1.L Protein, Dlk1 Protein
    Background
    Human sDLL-1 comprises the extracellular signaling domain of DLL1, a member of a structurally-related family of single-pass type I trans-membrane proteins that serve as ligands for Notch receptors. It is expressed in the heart and pancreas, and to a lesser extent in various other tissues. DLL-1 functions to specifically activate the Notch-1 and Notch-2 receptors.
    Alternative Names: sDLL-1 protein, Delta-like protein 1 protein, Delta-1 protein, sDLL1, sDLL 1 protein, sDLL 1, sDLL-1 protein, sDLL-1
    Molecular Weight
    57-60 kDa
    Pathways
    Notch Signaling, Stem Cell Maintenance
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