C12orf57 Protein
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- Target See all C12orf57 Proteins
- C12orf57 (Chromosome 12 Open Reading Frame 57 (C12orf57))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Sequence
- GLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA
- Characteristics
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Purified recombinant Mouse C10 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract Balb/c mouse spleen MNCs using a concentration range of 10.0-100.0 ng/mL. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product C12orf57 Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Supplied as a lyophilized powder.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- C12orf57 (Chromosome 12 Open Reading Frame 57 (C12orf57))
- Alternative Name
- C10 (C12orf57 Products)
- Synonyms
- MRP-1 Protein, Scya6 Protein, c10 Protein, 2310033H05Rik Protein, C10 Protein, GRCC10 Protein, TEMTYS Protein, c12orf57 Protein, fc02g04 Protein, wu:fc02g04 Protein, zgc:86838 Protein, chemokine (C-C motif) ligand 6 Protein, gene rich cluster, C10 gene Protein, chromosome 12 open reading frame 57 Protein, chromosome 5 open reading frame, human C12orf57 Protein, chromosome 12 open reading frame 57 L homeolog Protein, Ccl6 Protein, Grcc10 Protein, C12orf57 Protein, C5H12orf57 Protein, c12orf57.L Protein, grcc10 Protein
- Background
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Mouse C10 belongs to the CC chemokine family and is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL3 or IL4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 contains the four highly conserved cysteine residues present in CC chemokines. The mature protein contains 95 amino acid residues.
Alternative Names: C-10, MRP-1 protein, C10, C-10 protein, C 10, CCL6 protein, C 10 protein, C-10 protein - Molecular Weight
- 10.7 kDa
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