Cytokeratin 18 Protein
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- Target See all Cytokeratin 18 (KRT18) Proteins
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Control Peptide (CP)
- Characteristics
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Purified recombinant Human Cytokeratin 18 protein
Expression System: E.coli - Top Product
- Discover our top product KRT18 Protein
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Keratin 18 (KRT18) (AA 1-430) protein (His tag)
KRT18 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Keratin 18 (KRT18) (AA 1-430) protein (GST tag)KRT18 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Comment
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Protein standard in 1D and 2D SDS gel electrophoresis, Immunoassays, Immunization
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 175 μL distilled water (final volume 250 μL)
- Buffer
- Lyophilized from solution containing 30 mM Tris/HCI pH 8, 9.5 M urea, 2 mM DTT, 2 mM EDTA, and 10 mM methylammonium chloride.
- Precaution of Use
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
- Alternative Name
- Cytokeratin 18 (KRT18 Products)
- Background
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Cytokeratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Alternative Names: Cytokeratin 18 protein, Cytokeratin 18, Cytokeratin-18 protein, Cytokeratin-18, Keratin K18 protein, Cytokeratin 18 - Molecular Weight
- 45 kDa
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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