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BMP6 Protein

BMP6 Origin: Human Host: HEK-293 Cells Recombinant > 95 % pure Active
Catalog No. ABIN935246
  • Target See all BMP6 Proteins
    BMP6 (Bone Morphogenetic Protein 6 (BMP6))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 6
    • 3
    • 2
    Human
    Source
    • 7
    • 3
    • 1
    HEK-293 Cells
    Sequence
    VSSASDYNSS ELKTACRKHE LYVSFQDLGW QDWIIAPKGY AANYCDGECS FPLNAHMNAT NHAIVQTLVH LMNPEYVPKP CCAPTKLNAI SVLYFDDNSN VILKKYRNMV VRACGCH
    Characteristics
    Purified recombinant Human BMP6 protein
    Expression System: HEK cells
    Bioactivity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 this effect is 0.03-0.06 µg/mL.
    Purity
    > 95 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product BMP6 Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    Lyophilized from 10 mM Tris, pH 9.0.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    BMP6 (Bone Morphogenetic Protein 6 (BMP6))
    Alternative Name
    BMP6 (BMP6 Products)
    Synonyms
    BMP6 Protein, zgc:113595 Protein, vgr Protein, vgr-1 Protein, vgr1 Protein, VGR Protein, VGR1 Protein, D13Wsu115e Protein, Vgr1 Protein, bone morphogenetic protein 6 Protein, bone morphogenetic protein 6 S homeolog Protein, BMP6 Protein, bmp6 Protein, bmp6.S Protein, Bmp6 Protein
    Background
    TGF beta family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling and maintenance of a variety of other tissues and organs. Increasing evidence indicates that BMP-Smad signaling has a tumor suppressing activity and that BMPs can inhibit tumor growth. BMP-6 is abnormally expressed in breast cancer cell lines, however, its function in promoting breast cancer development is unknown.
    Alternative Names: BMP 6 protein, VGR protein, BMP6, Bone Morphogenetic protein 6 protein, BMP-6, BMP-6 protein, BMP-6 protein, BMP 6
    Molecular Weight
    26.2 kDa
    Pathways
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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