GDF6 Protein
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- Target See all GDF6 Proteins
- GDF6 (Growth Differentiation Factor 6 (GDF6))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR
- Characteristics
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Purified recombinant Human BMP13 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 µg/mL. - Purity
- > 95 % pure
- Endotoxin Level
- < 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product GDF6 Protein
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Growth Differentiation Factor 6 (GDF6) protein
GDF6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Growth Differentiation Factor 6 (GDF6) proteinGDF6 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Comment
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Biological activity: The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 μg/mL.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- Supplied lyophilized with no additives.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- GDF6 (Growth Differentiation Factor 6 (GDF6))
- Alternative Name
- BMP13 (GDF6 Products)
- Background
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BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains.
Alternative Names: BMP-13 protein, BMP-13, BMP 13, CDMP-2 protein, BMP-13 protein, Cartilage-Derived Morphogenetic Protein-2 protein, Bone Morphogenetic protein 13 protein, BMP13, GDF-6 protein, BMP 13 protein - Molecular Weight
- 27.5 kDa
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