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Defensin beta 3 Protein (DEFB3)

DEFB3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Catalog No. ABIN935229
  • Target See all Defensin beta 3 (DEFB3) Proteins
    Defensin beta 3 (DEFB3)
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 4
    • 3
    • 2
    • 1
    Human
    Source
    • 6
    • 2
    Escherichia coli (E. coli)
    Sequence
    GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
    Characteristics
    Purified recombinant Human BD3 protein
    Expression System: E.coli
    Bioactivity: Exhibits antimicrobial activity against gram-positive bacteria S. aureus and gram-negative P. aeruginosa and E.coli.
    Purity
    > 98 % pure
    Endotoxin Level
    < 0.1 ng per µg (1 EU/µg).
    Top Product
    Discover our top product DEFB3 Protein
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute in 10 mM Acetic Acid to a concentration of 0.1 - 1.0 mg/mL.
    Buffer
    Supplied lyophilized with no additives.
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
  • Target
    Defensin beta 3 (DEFB3)
    Alternative Name
    BD3 (DEFB3 Products)
    Synonyms
    BD-3 Protein, DEFB-3 Protein, DEFB103 Protein, DEFB3 Protein, HBD3 Protein, HBP-3 Protein, HBP3 Protein, hBD-3 Protein, BNBD-3 Protein, BNBD-6 Protein, BNDB-3 Protein, BNDB-6 Protein, BNDB3 Protein, DEFB103A Protein, DEFB2 Protein, DEFB6 Protein, bnbd3 Protein, defb405 Protein, defensin beta 103A Protein, defensin beta 3 Protein, beta-defensin 3 Protein, DEFB103A Protein, Defb3 Protein, DEFB3 Protein
    Background
    Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells.
    Alternative Names: BD-3 protein, BD 3, BD 3 protein, BD3, BD-3 protein, beta-defensin-3 protein, BD 3 protein, BD-3
    Molecular Weight
    3.9 kDa
    Pathways
    Production of Molecular Mediator of Immune Response
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