Defensin beta 3 Protein (DEFB3)
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- Target See all Defensin beta 3 (DEFB3) Proteins
- Defensin beta 3 (DEFB3)
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
- Characteristics
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Purified recombinant Human BD3 protein
Expression System: E.coli
Bioactivity: Exhibits antimicrobial activity against gram-positive bacteria S. aureus and gram-negative P. aeruginosa and E.coli. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product DEFB3 Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in 10 mM Acetic Acid to a concentration of 0.1 - 1.0 mg/mL.
- Buffer
- Supplied lyophilized with no additives.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- Defensin beta 3 (DEFB3)
- Alternative Name
- BD3 (DEFB3 Products)
- Synonyms
- BD-3 Protein, DEFB-3 Protein, DEFB103 Protein, DEFB3 Protein, HBD3 Protein, HBP-3 Protein, HBP3 Protein, hBD-3 Protein, BNBD-3 Protein, BNBD-6 Protein, BNDB-3 Protein, BNDB-6 Protein, BNDB3 Protein, DEFB103A Protein, DEFB2 Protein, DEFB6 Protein, bnbd3 Protein, defb405 Protein, defensin beta 103A Protein, defensin beta 3 Protein, beta-defensin 3 Protein, DEFB103A Protein, Defb3 Protein, DEFB3 Protein
- Background
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Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified, BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells.
Alternative Names: BD-3 protein, BD 3, BD 3 protein, BD3, BD-3 protein, beta-defensin-3 protein, BD 3 protein, BD-3 - Molecular Weight
- 3.9 kDa
- Pathways
- Production of Molecular Mediator of Immune Response
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