APOE Protein
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- Target See all APOE Proteins
- APOE (Apolipoprotein E (APOE))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSEQVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET RARLSKELQA AQARLGADME DVRGRLVQYR GEVQAMLGQS TEELRVRLAS HLRKLRKRLL RDADDLQKRL AVYQAGAREG AERGLSAIRE RLGPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRDRL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKVQAAVGT SAAPVPSDNH
- Characteristics
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Purified recombinant Human ApoE4 protein
Expression System: E.coli - Purity
- > 90 % pure
- Endotoxin Level
- < 0.1 ng per µg(1 EU/µg).
- Top Product
- Discover our top product APOE Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
- Buffer
- Lyophilized from 20 mM Na3PO4, pH 7.8.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- APOE (Apolipoprotein E (APOE))
- Alternative Name
- ApoE4 (APOE Products)
- Synonyms
- ad2 Protein, apoprotein Protein, im:7036787 Protein, wu:fb69a05 Protein, zgc:110064 Protein, apoe Protein, AI255918 Protein, AD2 Protein, LDLCQ5 Protein, LPG Protein, APOEA Protein, Apo-E Protein, apolipoprotein E Protein, apolipoprotein Ea Protein, apoe Protein, apoea Protein, Apoe Protein, APOE Protein
- Background
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ApoE4 is the high risk variant of the APOE gene, the gene most associated with increased risk for late-onset Alzheimer's disease. Wikipedia shows that it is not a direct determinant of the disease - at least a third of patients with Alzheimer's disease are ApoE4 negative and some ApoE4 homozygotes never develop the disease. Yet those with ApoE4/ApoE4 have ~20x risk of developing Alzheimer's.
Alternative Names: Apo E4 protein, Apo-A4 protein, ApoE-4, ApoE 4 protein, ApoE-4 protein, Apolipoprotein E4 protein, ApoE 4, ApoE4 - Molecular Weight
- 34.4 kDa
- Pathways
- Regulation of Cell Size, Lipid Metabolism
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