FLIP Protein (AA 1-480)

Catalog No. ABIN935116

Product Details

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Protein Type: Recombinant

Protein Characteristics: AA 1-480

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MSAEVIHQVE EALDTDEKEM LLFLCRDVAI DVVPPNVRDL LDILRERGKL SVGDLAELLY RVRRFDLLKR ILKMDRKAVE THLLRNPHLV SDYRVLMAEI GEDLDKSDVS SLIFLMKDYM GRGKISKEKS FLDLVVELEK LNLVAPDQLD LLEKCLKNIH RIDLKTKIQK YKQSVQGAGT SYRNVLQAAI QKSLKDPSNN FRLHNGRSKE QRLKEQLGAQ QEPVKKSIQE SEAFLPQSIP EERYKMKSKP LGICLIIDCI GNETELLRDT FTSLGYEVQK FLHLSMHGIS QILGQFACMP EHRDYDSFVC VLVSRGGSQS VYGVDQTHSG LPLHHIRRMF MGDSCPYLAG KPKMFFIQNY VVSEGQLENS SLLEVDGPAM KNVEFKAQKR GLCTVHREAD FFWSLCTADM SLLEQSHSSP SLYLQCLSQK LRQERKRPLL DLHIELNGYM YDWNSRVSAK EKYYVWLQHT LRKKLILSYT

Characteristics: Recombinant human CFLAR protein
Expression System: E.coli

Purity: > 85 % pure

Application Details

Application Notes: CFLAR protein has been used in SDS PAGE, and may be suitable for use in other assays

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. 20 mM Tris-HCl buffer (pH8.0) containing 10 % glycerol.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Can be stored at 4 °C short term (1-2 weeks). For long term storage, aliquot and store at -20 °C or -70 °C.

Target Details

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Alternative Name: CFLAR (CFLAR Products)

Background: CFLAR, also known as FLIP, is involved in the regulation of apoptosis. It has been designated by independent groups as Casper, I-FLICE, CLARP, FLAME-1 and MRIT. Although its exact role is still being elucidated, it appears to be an important factor in the regulation of apoptosis downstream of all known death receptors. Recombinant human CFLAR protein was expressed in E.coli and denatured using detergent during a conventional chromatography purification process.
Alternative Names: c-FLIP protein, USURPIN protein, I-FLICE protein, FLIP protein, CLARP protein, MRIT protein, FLAME protein, Casper protein, FLAME1 protein, FLAME-1 protein, CASP8 and FADD-like apoptosis regulator protein, CASH protein

Molecular Weight: 55.3 kDa (480 AA)

Pathways: Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development