CAPG Protein (AA 1-348)

Catalog No. ABIN935076

Product Details

Target: CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))

Protein Type: Recombinant

Protein Characteristics: AA 1-348

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Sequence: MYTAIPQSGS PFPGSVQDPG LHVWRVEKLK PVPVAQENQG VFFSGDSYLV LHNGPEEVSH LHLWIGQQSS RDEQGACAVL AVHLNTLLGE RPVQHREVQG NESDLFMSYF PRGLKYQEGG VESAFHKTST GAPAAIKKLY QVKGKKNIRA TERALNWDSF NTGDCFILDL GQNIFAWCGG KSNILERNKA RDLALAIRDS ERQGKAQVEI VTDGEEPAEM IQVLGPKPAL KEGNPEEDLT ADKANAQAAA LYKVSDATGQ MNLTKVADSS PFALELLISD DCFVLDNGLC GKIYIWKGRK ANEKERQAAL QVAEGFISRM QYAPNTQVEI LPQGRESPIF KQFFKDWK

Characteristics: Purified recombinant Human CAPG protein
Expression System: E.coli

Purity: > 95 % pure

Application Details

Application Notes: CAPG protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0 mM DTT, and 10 % glycerol.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: RT/-20 °C

Storage Comment: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Target Details

Target: CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))

Alternative Name: CAPG (CAPG Products)

Synonyms: AFCP Protein, MCP Protein, gCap39 Protein, mbh1 Protein, capping actin protein, gelsolin like Protein, capping protein (actin filament), gelsolin-like Protein, CAPG Protein, Capg Protein

Background: Macrophage-capping protein, also known as CAPG, belongs to the gelsolin/villin family of actin-regulatory proteins. CAPG is a calcium-sensitive DNA-binding protein that plays a role in macrophage function. It is expressed in macrophages and macrophage-like cells and can localize both to the nucleus and the cytoplasm. This protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. Recombinant human CAPG was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: Capping protein gelsolin like protein, Myc basic motif homolog 1., Actin regulatory protein CAP G protein, gCap39 protein, MCP protein, CAPG protein, Macrophage capping protein protein, mbh1 protein, Gelsolin like capping protein protein, AFCP protein, Macrophage-capping protein Actin capping protein GCAP39 protein, Capping protein (actin filament) gelsolin like protein

Molecular Weight: 38.5 kDa (348 AA)

Pathways: Regulation of Actin Filament Polymerization