Ketohexokinase Protein (KHK) (AA 1-298)
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- Target See all Ketohexokinase (KHK) Proteins
- Ketohexokinase (KHK)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-298
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MEEKQILCVG LVVLDVISLV DKYPKEDSEI RCLSQRWQRG GNASNSCTIL SLLGAPCAFM GSMAPGHVAD FVLDDLRRYS VDLRYTVFQT TGSVPIATVI INEASGSRTI LYYDRSLPDV SATDFEKVDL TQFKWIHIEG RNASEQVKML QRIDAHNTRQ PPEQKIRVSV EVEKPREELF QLFGYGDVVF VSKDVAKHLG FQSAEEALRG LYGRVRKGAV LVCAWAEEGA DALGPDGKLL HSDAFPPPRV VDTLGAGDTF NASVIFSLSQ GRSVQEALRF GCQVAGKKCG LQGFDGIV
- Characteristics
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Purified recombinant Human Ketohexokinase protein
Expression System: E.coli - Purity
- > 90 % pure
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- Application Notes
- Ketohexokinase protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Supplied as a liquid in PBS, pH 7.4, containing 10 % glycerol.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
- Storage Comment
- Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
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- Target
- Ketohexokinase (KHK)
- Alternative Name
- Ketohexokinase (KHK Products)
- Synonyms
- wu:fj68h03 Protein, zgc:92219 Protein, zgc:92626 Protein, KHK Protein, khk Protein, KETHPRO Protein, ketohexokinase Protein, Ketohexokinase Protein, KHK Protein, khk Protein, Hhal_0921 Protein, AaeL_AAEL006316 Protein, Nwat_0240 Protein, Khk Protein
- Background
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Ketohexokinase is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate, leading to consumption of ATP, formation of AMP. This protein initiates first step in the metabolism of dietary fructose and is an important regulator of hepatic glucose metabolism. It is highly found in liver, renal cortex, and small intestine. Its deficiency causes the benign hereditary metabolic disorder essential fructosuria, leading to fructose being excreted in the urine. Recombinant human Ketohexokinase was expressed in E. coli and purified by using conventional chromatography.
Alternative Names: Hepatic fructokinase protein, EC 2.7.1.3 protein, KHK protein, , Hepatic fructokinase protein, ketohexokinase protein, Ketohexokinase isoform a protein - Molecular Weight
- 32.7 kDa (298 AA)
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